Assessment of Structural Intolerance and Durability
General Structure Information 2wfq DHH crystal structure of the n-terminal signalling domain of human dhh without calcium 1.85Å AUTH B.BISHOP,A.R.ARICESCU,K.HARLOS,C.A.OCALLAGHAN,E.Y.JONES,AUTH 2 C.SIEBOLDTITL STRUCTURAL INSIGHTS INTO HEDGEHOG LIGAND SEQUESTRATION BYTITL 2 THE HUMAN HEDGEHOG-INTERACTING PROTEIN HIPREF NAT.STRUCT.MOL.BIOL. V. 16 698 2009REFN ISSN 1545-9993PMID 19561611DOI 10.1038/NSMB.1607 Variant Set Distributions Mapped Variants
General Structure Information 1zjk MASP2 crystal structure of the zymogen catalytic region of human masp-2 2.18Å AUTH P.GAL,V.HARMAT,A.KOCSIS,T.BIAN,L.BARNA,G.AMBRUS,B.VEGH,AUTH 2 J.BALCZER,R.B.SIM,G.NARAY-SZABO,P.ZAVODSZKYTITL A TRUE AUTOACTIVATING ENZYME: STRUCTURAL INSIGHT INTOTITL 2 MANNOSE-BINDING LECTIN-ASSOCIATED SERINE PROTEASE-2TITL 3 ACTIVATIONSREF J.BIOL.CHEM. V. 280 33435 2005REFN ISSN 0021-9258PMID 16040602DOI 10.1074/JBC.M506051200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3l4v MGAM crystal complex of n-terminal human maltase-glucoamylase with kotalanol 2.1Å AUTH L.SIM,K.JAYAKANTHAN,S.MOHAN,R.NASI,B.D.JOHNSTON,AUTH 2 B.M.PINTO,D.R.ROSETITL NEW GLUCOSIDASE INHIBITORS FROM AN AYURVEDIC HERBALTITL 2 TREATMENT FOR TYPE 2 DIABETES: STRUCTURES ANDTITL 3 INHIBITION OF HUMAN INTESTINAL MALTASE-GLUCOAMYLASETITL 4 WITH COMPOUNDS FROM SALACIA RETICULATA.REF BIOCHEMISTRY V. 49 443 2010REFN ISSN 0006-2960PMID 20039683DOI 10.1021/BI9016457 Variant […]
General Structure Information 4c0d CNOT1 structure of the not module of the human ccr4-not complex (cnot1-cnot2-cnot3) 3.2Å AUTH A.BOLAND,Y.CHEN,T.RAISCH,S.JONAS,D.KUZUOGLU-OZTURK,AUTH 2 L.WOHLBOLD,O.WEICHENRIEDER,E.IZAURRALDETITL STRUCTURE AND ASSEMBLY OF THE NOT MODULE OF THE HUMANTITL 2 CCR4-NOT COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 20 1289 2013REFN ISSN 1545-9993PMID 24121232DOI 10.1038/NSMB.2681 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]