Assessment of Structural Intolerance and Durability
General Structure Information 1uqs CD1B the crystal structure of human cd1b with a bound bacterial glycolipid 3.1Å AUTH T.BATUWANGALA,D.SHEPHERD,S.D.GADOLA,K.J.C.GIBSON,AUTH 2 N.R.ZACCAI,A.R.FERSHT,G.S.BESRA,V.CERUNDOLO,AUTH 3 E.Y.JONESTITL THE CRYSTAL STRUCTURE OF HUMAN CD1B WITH A BOUNDTITL 2 BACTERIAL GLYCOLIPIDREF J.IMMUNOL. V. 172 2382 2004REFN ISSN 0022-1767PMID 14764708 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3f8u PDIA3 tapasin/erp57 heterodimer 2.6Å AUTH G.DONG,P.A.WEARSCH,D.R.PEAPER,P.CRESSWELL,K.M.REINISCHTITL INSIGHTS INTO MHC CLASS I PEPTIDE LOADING FROM THE STRUCTURETITL 2 OF THE TAPASIN-ERP57 THIOL OXIDOREDUCTASE HETERODIMER.REF IMMUNITY V. 30 21 2009REFN ISSN 1074-7613PMID 19119025DOI 10.1016/J.IMMUNI.2008.10.018 Variant Set Distributions Mapped Variants
General Structure Information 3es6 PIP crystal structure of the novel complex formed between zinc 2- glycoprotein (zag) and prolactin inducible protein (pip) from human seminal plasma 3.23Å AUTH M.I.HASSAN,S.BILGRAMI,V.KUMAR,N.SINGH,S.YADAV,P.KAUR,AUTH 2 T.P.SINGHTITL CRYSTAL STRUCTURE OF THE NOVEL COMPLEX FORMED BETWEEN ZINCTITL 2 ALPHA2-GLYCOPROTEIN (ZAG) AND PROLACTIN-INDUCIBLE PROTEINTITL 3 (PIP) FROM HUMAN SEMINAL PLASMAREF J.MOL.BIOL. V. 384 […]
General Structure Information 3cxe CSF2RA structure of the gm-csf receptor complex 3.3Å AUTH G.HANSEN,T.R.HERCUS,B.J.MCCLURE,F.C.STOMSKI,M.DOTTORE,AUTH 2 J.POWELL,H.RAMSHAW,J.M.WOODCOCK,Y.XU,M.GUTHRIDGE,AUTH 3 W.J.MCKINSTRY,A.F.LOPEZ,M.W.PARKERTITL THE STRUCTURE OF THE GM-CSF RECEPTOR COMPLEX REVEALS ATITL 2 DISTINCT MODE OF CYTOKINE RECEPTOR ACTIVATIONREF CELL(CAMBRIDGE,MASS.) V. 134 496 2008REFN ISSN 0092-8674PMID 18692472DOI 10.1016/J.CELL.2008.05.053 Variant Set Distributions Mapped Variants
General Structure Information 3di2 IL7R crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain 2.7Å AUTH C.A.MCELROY,J.A.DOHM,S.T.WALSHTITL STRUCTURAL AND BIOPHYSICAL STUDIES OF THE HUMANTITL 2 IL-7/IL-7RALPHA COMPLEX.REF STRUCTURE V. 17 54 2009REFN ISSN 0969-2126PMID 19141282DOI 10.1016/J.STR.2008.10.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3di2 IL7 crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain 2.7Å AUTH C.A.MCELROY,J.A.DOHM,S.T.WALSHTITL STRUCTURAL AND BIOPHYSICAL STUDIES OF THE HUMANTITL 2 IL-7/IL-7RALPHA COMPLEX.REF STRUCTURE V. 17 54 2009REFN ISSN 0969-2126PMID 19141282DOI 10.1016/J.STR.2008.10.019 Variant Set Distributions Mapped Variants
General Structure Information 3h6a ITGB4 structure of the calx-beta domain of integrin beta4 crystallized in the presence of calcium 1.61Å AUTH N.ALONSO-GARCIA,A.INGLES-PRIETO,A.SONNENBERG,AUTH 2 J.M.DE PEREDATITL STRUCTURE OF THE CALX-BETA DOMAIN OF THE INTEGRINTITL 2 BETA4 SUBUNIT: INSIGHTS INTO FUNCTION ANDTITL 3 CATION-INDEPENDENT STABILITYREF ACTA CRYSTALLOGR.,SECT.D V. 65 858 2009REFN ISSN 0907-4449PMID 19622870DOI 10.1107/S0907444909018745 Variant Set […]
General Structure Information 3igu NAGA crystal structure of human alpha-n-acetylgalactosaminidase, covalent intermediate 2.15Å AUTH N.E.CLARK,S.C.GARMANTITL THE 1.9 A STRUCTURE OF HUMANTITL 2 ALPHA-N-ACETYLGALACTOSAMINIDASE: THE MOLECULAR BASIS OFTITL 3 SCHINDLER AND KANZAKI DISEASESREF J.MOL.BIOL. V. 393 435 2009REFN ISSN 0022-2836PMID 19683538DOI 10.1016/J.JMB.2009.08.021 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1itb IL1R1 type-1 interleukin-1 receptor complexed with interleukin-1 beta 2.5Å AUTH G.P.VIGERS,L.J.ANDERSON,P.CAFFES,B.J.BRANDHUBERTITL CRYSTAL STRUCTURE OF THE TYPE-I INTERLEUKIN-1TITL 2 RECEPTOR COMPLEXED WITH INTERLEUKIN-1BETA.REF NATURE V. 386 190 1997REFN ISSN 0028-0836PMID 9062193DOI 10.1038/386190A0 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ksr CHRNB2 nmr structures of tm domain of the n-acetylcholine receptor b2 subunit -1.0Å AUTH V.BONDARENKO,T.TILLMAN,Y.XU,P.TANGTITL NMR STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THETITL 2 N-ACETYLCHOLINE RECEPTOR BETA2 SUBUNIT.REF BIOCHIM.BIOPHYS.ACTA V.1798 1608 2010REFN ISSN 0006-3002PMID 20441771DOI 10.1016/J.BBAMEM.2010.04.014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants