Assessment of Structural Intolerance and Durability
General Structure Information 2qfz TBC1D22A crystal structure of human tbc1 domain family member 22a 2.1Å AUTH Y.TONG,W.TEMPEL,S.DIMOV,A.DONG,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN TBC1 DOMAIN FAMILYTITL 2 MEMBER 22A.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dme PHF3 solution structure of the tfiis domain ii of human phd finger protein 3 -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,S.WATABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TFIIS DOMAIN II OF HUMANTITL 2 PHD FINGER PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ut1 L3MBTL3 crystal structure of the 3-mbt repeat domain of l3mbtl3 2.05Å AUTH N.ZHONG,W.TEMPEL,A.K.WERNIMONT,S.GRASLUND,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,P.J.BROWNTITL CRYSTAL STRUCTURE OF THE 3-MBT REPEAT DOMAIN OF L3MBTL3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2iqj SMAP2 crystal structure of the gap domain of smap1l (loc64744) stromal membrane-associated protein 1-like 1.9Å AUTH Y.TONG,S.DIMOV,L.SHEN,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL STRUCTURE OF THE GAP DOMAIN OF SMAP1L (LOC64744)TITL 2 STROMAL MEMBRANE-ASSOCIATED PROTEIN 1-LIKEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2i1n DLG3 crystal structure of the 1st pdz domain of human dlg3 1.85Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,C.PHILLIPS,AUTH 2 C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINED WITH THETITL 2 HELP OF SELF-BINDING C-TERMINAL EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 4juy RNF31 crystal structure of the pub domain of e3 ubiquitin ligase rnf31 2.4Å AUTH J.HU,A.DONG,Y.LI,A.WERNIMONT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,Y.TONGTITL CRYSTAL STRUCTURE OF THE PUB DOMAIN OF E3 UBIQUITIN LIGASETITL 2 RNF31REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2ytw HTRA1 solution structure of the pdz-domain of human protease htra 1 precursor -1.0Å AUTH A.K.GORONCY,K.SAITO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ-DOMAIN OF HUMANTITL 2 PROTEASE HTRA 1 PRECURSORREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2lmd PROX1 minimal constraints solution nmr structure of prospero homeobox protein 1 from homo sapiens, northeast structural genomics consortium target hr4660b -1.0Å AUTH O.F.LANGE,P.ROSSI,N.G.SGOURAKIS,Y.SONG,H.W.LEE,J.M.ARAMINI,AUTH 2 A.ERTEKIN,R.XIAO,T.B.ACTON,G.T.MONTELIONE,D.BAKERTITL DETERMINATION OF SOLUTION STRUCTURES OF PROTEINS UP TO 40TITL 2 KDA USING CS-ROSETTA WITH SPARSE NMR DATA FROM DEUTERATEDTITL 3 SAMPLES.REF PROC.NATL.ACAD.SCI.USA V. 109 10873 2012REFN […]
General Structure Information 2cpx RBM41 solution structure of rna binding domain in hypothetical protein flj11016 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 HYPOTHETICAL PROTEIN FLJ11016REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ou2 KAT5 acetyltransferase domain of human hiv-1 tat interacting protein, 60kda, isoform 3 2.3Å AUTH H.WU,J.MIN,L.DOMBROVSKI,P.LOPPNAU,J.WEIGELT,AUTH 2 M.SUNDSTROM,C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF ACETYLTRANSFERASE DOMAINTITL 2 OF HUMAN HIV-1 TAT INTERACTING PROTEIN IN COMPLEXTITL 3 WITH ACETYLCOENZYME A.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants