General Structure Information
| PDB ID | 2ytw |
| HGNC Gene Label(s) | HTRA1 |
| Structure Name | solution structure of the pdz-domain of human protease htra 1 precursor |
| Resolution | -1.0Å |
| Reference | AUTH A.K.GORONCY,K.SAITO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ-DOMAIN OF HUMANTITL 2 PROTEASE HTRA 1 PRECURSORREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 111 |
| Number Of SNVs | 32 |
| Number Of Permutations | 4120 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.343 |
| p-value | 0.324 |
COSMIC
| Number Of Residues | 111 |
| Number Of SNVs | 4 |
| Number Of Permutations | 26 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 0.169 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.159 |
| p-value | 0.075 |