Assessment of Structural Intolerance and Durability
General Structure Information 2bmj AGAP2 gtpase like domain of centaurin gamma 1 (human) 2.1Å AUTH M.SOUNDARARAJAN,X.YANG,J.M.ELKINS,F.SOBOTT,D.A.DOYLETITL THE CENTAURIN GAMMA-1 GTPASE-LIKE DOMAIN FUNCTIONS AS ANTITL 2 NTPASE.REF BIOCHEM.J. V. 401 679 2007REFN ISSN 0264-6021PMID 17037982DOI 10.1042/BJ20060555 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3kuq DLC1 crystal structure of the dlc1 rhogap domain 2.3Å AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,F.MACKENZIE,L.SHEN,AUTH 2 N.ZHONG,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,AUTH 3 J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE DLC1 RHOGAP DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2k2d RCHY1 solution nmr structure of c-terminal domain of human pirh2. northeast structural genomics consortium (nesg) target ht2c -1.0Å AUTH Y.SHENG,R.C.LAISTER,A.LEMAK,B.WU,E.TAI,S.DUAN,AUTH 2 J.LUKIN,M.SUNNERHAGEN,S.SRISAILAM,M.KARRA,AUTH 3 S.BENCHIMOL,C.H.ARROWSMITHTITL MOLECULAR BASIS OF PIRH2-MEDIATED P53TITL 2 UBIQUITYLATION.REF NAT.STRUCT.MOL.BIOL. V. 15 1334 2008REFN ISSN 1545-9993PMID 19043414DOI 10.1038/NSMB.1521 Variant Set Distributions Mapped Variants
General Structure Information 2b9e NSUN5 human nsun5 protein 1.65Å AUTH J.R.MIN,H.WU,H.ZENG,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN NSUN5 PROTEIN INTITL 2 COMPLEX WITH S-ADENOSYL-L-METHIONINEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2r2q GABARAPL1 crystal structure of human gamma-aminobutyric acid receptor- associated protein-like 1 (gabarap1), isoform cra_a 1.65Å AUTH R.PARAMANATHAN,T.DAVIS,W.TEMPEL,S.MUJIB,AUTH 2 C.BUTLER-COLE,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,S.DHE-PAGANONTITL CRYSTAL STRUCTURE OF HUMAN GAMMA-AMINOBUTYRIC ACIDTITL 2 RECEPTOR-ASSOCIATED PROTEIN-LIKE 1 (GABARAP1),TITL 3 ISOFORM CRA_A.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wgl TOLLIP solution structure of cue domain in the c-terminal of human toll-interacting protein (tollip) -1.0Å AUTH C.ZHAO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF CUE DOMAIN IN THE C-TERMINALTITL 2 OF HUMAN TOLL-INTERACTING PROTEIN (TOLLIP)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2eq3 ZNF347 solution structure of the 17th c2h2 type zinc finger domain of zinc finger protein 347 -1.0Å AUTH K.FUTAMI,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 17TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kvh NUDT16L1 crystal structure of human protein syndesmos (nudt16-like protein) 1.7Å AUTH L.TRESAUGUES,M.I.SIPONEN,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,A.KALLAS,AUTH 4 T.KARLBERG,T.KOTENYOVA,A.KOTZSCH,P.KRAULIS,M.MOCHE,AUTH 5 T.K.NIELSEN,T.NYMAN,C.PERSSON,A.K.ROOS,H.SCHULER,P.SCHUTZ,AUTH 6 A.G.THORSELL,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN PROTEIN SYNDESMOS (NUDT16L1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmy STRBP solution structure of dsrm domain in spermatid perinuclear rna-bind protein -1.0Å AUTH S.KADIRVEL,F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,AUTH 2 T.TERADA,S.YOKOYAMATITL SOLUTION STRUCTURE OF DSRM DOMAIN IN SPERMATIDTITL 2 PERINUCLEAR RNA-BIND PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dnp RBM14 solution structure of rna binding domain 2 in rna-binding protein 14 -1.0Å AUTH M.KUSUHARA,K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,AUTH 2 T.TERADA,M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN 2 INTITL 2 RNA-BINDING PROTEIN 14REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants