3KUQ.A | DLC1

General Structure Information

PDB ID 3kuq
HGNC Gene Label(s) DLC1
Structure Name crystal structure of the dlc1 rhogap domain
Resolution 2.3Å
Reference AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,F.MACKENZIE,L.SHEN,AUTH 2 N.ZHONG,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,AUTH 3 J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE DLC1 RHOGAP DOMAINREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 187
Number Of SNVs 59
Number Of Permutations 5305
Optimal Distance Threshold 6.0
K Statistic 0.027
p-value 0.783
COSMIC

Number Of Residues 187
Number Of SNVs 3
Number Of Permutations 46
Optimal Distance Threshold 8.0
K Statistic 0.667
p-value 0.012

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants