General Structure Information
| PDB ID | 2bmj |
| HGNC Gene Label(s) | AGAP2 |
| Structure Name | gtpase like domain of centaurin gamma 1 (human) |
| Resolution | 2.1Å |
| Reference | AUTH M.SOUNDARARAJAN,X.YANG,J.M.ELKINS,F.SOBOTT,D.A.DOYLETITL THE CENTAURIN GAMMA-1 GTPASE-LIKE DOMAIN FUNCTIONS AS ANTITL 2 NTPASE.REF BIOCHEM.J. V. 401 679 2007REFN ISSN 0264-6021PMID 17037982DOI 10.1042/BJ20060555 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 173 |
| Number Of SNVs | 39 |
| Number Of Permutations | 19859 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.022 |
| p-value | 0.96 |
COSMIC
| Number Of Residues | 173 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.868 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.383 |
| p-value | 0.711 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
