Assessment of Structural Intolerance and Durability
General Structure Information 3r8k HEBP2 crystal structure of human soul protein (hexagonal form) 2.85Å AUTH E.AMBROSI,S.CAPALDI,M.BOVI,G.SACCOMANI,M.PERDUCA,H.L.MONACOTITL STRUCTURAL CHANGES IN THE BH3 DOMAIN OF SOUL PROTEIN UPONTITL 2 INTERACTION WITH THE ANTI-APOPTOTIC PROTEIN BCL-XL.REF BIOCHEM.J. V. 438 291 2011REFN ISSN 0264-6021PMID 21639858DOI 10.1042/BJ20110257 Variant Set Distributions Mapped Variants
General Structure Information 1wyo MAPRE3 solution structure of the ch domain of human microtubule- associated protein rp/eb family member 3 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBERTITL 3 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yhw GNE high-resolution crystal structures of n-acetylmannosamine kinase: insights about substrate specificity, activity and inhibitor modelling. 1.64Å AUTH J.MARTINEZ,L.D.NGUYEN,E.TAUBERGER,S.HINDERLICH,W.REUTTER,AUTH 2 H.FAN,W.SAENGER,S.MONIOTTITL CRYSTAL STRUCTURES OF N-ACETYLMANNOSAMINE KINASE PROVIDETITL 2 INSIGHTS INTO ENZYME SPECIFICITY AND INHIBITIONREF J.BIOL.CHEM. V. 287 13656 2012REFN ISSN 0021-9258PMID 22343627DOI 10.1074/JBC.M111.318170 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2lkt RARRES3 solution structure of n-terminal domain of human tig3 in 2 m urea -1.0Å AUTH L.WANG,W.YU,X.REN,J.LIN,C.JIN,B.XIATITL (1)H, (13)C, AND (15)N RESONANCE ASSIGNMENTS OF THETITL 2 N-TERMINAL DOMAIN OF HUMAN TIG3REF BIOMOL.NMR ASSIGN. V. 6 201 2012REFN ISSN 1874-2718PMID 22290676DOI 10.1007/S12104-012-9357-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2edp SHROOM4 solution structure of the pdz domain from human shroom family member 4 -1.0Å AUTH H.ENDO,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 SHROOM FAMILY MEMBER 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4doh IL20RA il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4doh IL20 il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1m6d CTSF crystal structure of human cathepsin f 1.7Å AUTH J.R.SOMOZA,J.T.PALMER,J.D.HOTITL THE CRYSTAL STRUCTURE OF HUMAN CATHEPSIN F AND ITSTITL 2 IMPLICATIONS FOR THE DEVELOPMENT OF NOVEL IMMUNOMODULATORSREF J.MOL.BIOL. V. 322 559 2002REFN ISSN 0022-2836PMID 12225749DOI 10.1016/S0022-2836(02)00780-5 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jw5 POLL polymerase lambda brct domain -1.0Å AUTH G.A.MUELLER,A.F.MOON,E.F.DEROSE,B.J.DAVIS,AUTH 2 D.A.RAMSDEN,L.C.PEDERSEN,R.E.LONDONTITL POLYMERASE LAMBDA BRCT DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3a6p XPO5 crystal structure of exportin-5:rangtp:pre-mirna complex 2.92Å AUTH C.OKADA,E.YAMASHITA,S.J.LEE,S.SHIBATA,J.KATAHIRA,A.NAKAGAWA,AUTH 2 Y.YONEDA,T.TSUKIHARATITL A HIGH-RESOLUTION STRUCTURE OF THE PRE-MICRORNA NUCLEARTITL 2 EXPORT MACHINERYREF SCIENCE V. 326 1275 2009REFN ISSN 0036-8075PMID 19965479DOI 10.1126/SCIENCE.1178705 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants