Assessment of Structural Intolerance and Durability
General Structure Information 3ihr UCHL5 crystal structure of uch37 2.95Å AUTH S.E.BURGIE,C.A.BINGMAN,A.B.SONI,G.N.PHILLIPSTITL STRUCTURAL CHARACTERIZATION OF HUMAN UCH37.REF PROTEINS 2011REFN ESSN 1097-0134PMID 21953935DOI 10.1002/PROT.23147 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2lgr OARD1 solution structure of human protein c6orf130, a putative macro domain -1.0Å AUTH F.C.PETERSON,D.CHEN,B.L.LYTLE,M.N.ROSSI,I.AHEL,J.M.DENU,AUTH 2 B.F.VOLKMANTITL ORPHAN MACRODOMAIN PROTEIN (HUMAN C6ORF130) IS ANTITL 2 O-ACYL-ADP-RIBOSE DEACYLASE: SOLUTION STRUCTURE ANDTITL 3 CATALYTIC PROPERTIES.REF J.BIOL.CHEM. V. 286 35955 2011REFN ISSN 0021-9258PMID 21849506DOI 10.1074/JBC.M111.276238 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4krf AGO1 structure of human argonaute-1 let-7 complex 2.1Å AUTH C.R.FAEHNLE,E.ELKAYAM,A.D.HAASE,G.J.HANNON,L.JOSHUA-TORTITL THE MAKING OF A SLICER: ACTIVATION OF HUMAN ARGONAUTE-1.REF CELL REP V. 3 1901 2013REFN ESSN 2211-1247PMID 23746446DOI 10.1016/J.CELREP.2013.05.033 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2h1s GRHPR crystal structure of a glyoxylate/hydroxypyruvate reductase from homo sapiens 2.45Å AUTH E.BITTO,G.E.WESENBERG,G.N.PHILLIPS JR.,C.A.BINGMAN,AUTH 2 CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL CRYSTAL STRUCTURE OF A GLYOXYLATE/HYDROXYPYRUVATE REDUCTASETITL 2 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ab1 AAMDC x-ray structure of gene product from homo sapiens hs.95870 2.59Å AUTH CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL X-RAY STRUCTURE OF GENE PRODUCT FROM HOMO SAPIENS HS.95870REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2q4k C11orf68 ensemble refinement of the protein crystal structure of gene product from homo sapiens hs.433573 2.5Å AUTH E.J.LEVIN,D.A.KONDRASHOV,G.E.WESENBERG,G.N.PHILLIPSTITL ENSEMBLE REFINEMENT OF PROTEIN CRYSTAL STRUCTURES:TITL 2 VALIDATION AND APPLICATION.REF STRUCTURE V. 15 1040 2007REFN ISSN 0969-2126PMID 17850744DOI 10.1016/J.STR.2007.06.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dcy C12orf5 crystal structure a tp53-induced glycolysis and apoptosis regulator protein from homo sapiens. 1.75Å AUTH J.G.MCCOY,C.A.BINGMAN,G.E.WESENBERG,AUTH 2 G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE A TP53-INDUCED GLYCOLYSIS ANDTITL 2 APOPTOSIS REGULATOR PROTEIN FROM HOMO SAPIENS.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2e9x GINS3 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Mapped Variants
General Structure Information 2e9x GINS4 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]