General Structure Information
| PDB ID | 4krf |
| HGNC Gene Label(s) | AGO1 |
| Structure Name | structure of human argonaute-1 let-7 complex |
| Resolution | 2.1Å |
| Reference | AUTH C.R.FAEHNLE,E.ELKAYAM,A.D.HAASE,G.J.HANNON,L.JOSHUA-TORTITL THE MAKING OF A SLICER: ACTIVATION OF HUMAN ARGONAUTE-1.REF CELL REP V. 3 1901 2013REFN ESSN 2211-1247PMID 23746446DOI 10.1016/J.CELREP.2013.05.033 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 817 |
| Number Of SNVs | 81 |
| Number Of Permutations | 26897 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.033 |
| p-value | 0.971 |
COSMIC
| Number Of Residues | 817 |
| Number Of SNVs | 10 |
| Number Of Permutations | 3582 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.111 |
| p-value | 0.374 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 81 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.044 |
| p-value | 0.53 |