General Structure Information 2eb1 DICER1 crystal structure of the c-terminal rnase iii domain of human dicer 2.0Å AUTH D.TAKESHITA,S.ZENNO,W.C.LEE,K.NAGATA,K.SAIGO,M.TANOKURATITL HOMODIMERIC STRUCTURE AND DOUBLE-STRANDED RNA CLEAVAGETITL 2 ACTIVITY OF THE C-TERMINAL RNASE III DOMAIN OF HUMAN DICERREF J.MOL.BIOL. V. 374 106 2007REFN ISSN 0022-2836PMID 17920623DOI 10.1016/J.JMB.2007.08.069 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2zix MUS81 crystal structure of the mus81-eme1 complex 3.5Å AUTH J.H.CHANG,J.J.KIM,J.M.CHOI,J.H.LEE,Y.CHOTITL CRYSTAL STRUCTURE OF THE MUS81-EME1 COMPLEXREF GENES DEV. V. 22 1093 2008REFN ISSN 0890-9369PMID 18413719DOI 10.1101/GAD.1618708 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2gw6 TSEN15 nmr structure of the human trna endonuclease sen15 subunit -1.0Å AUTH J.SONG,J.L.MARKLEYTITL THREE-DIMENSIONAL STRUCTURE DETERMINED FOR ATITL 2 SUBUNIT OF HUMAN TRNA SPLICING ENDONUCLEASETITL 3 (SEN15) REVEALS A NOVEL DIMERIC FOLD.REF J.MOL.BIOL. V. 366 155 2007REFN ISSN 0022-2836PMID 17166513DOI 10.1016/J.JMB.2006.11.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2ziv EME1 crystal structure of the mus81-eme1 complex 2.7Å AUTH J.H.CHANG,J.J.KIM,J.M.CHOI,J.H.LEE,Y.CHOTITL CRYSTAL STRUCTURE OF THE MUS81-EME1 COMPLEXREF GENES DEV. V. 22 1093 2008REFN ISSN 0890-9369PMID 18413719DOI 10.1101/GAD.1618708 Variant Set Distributions Mapped Variants
General Structure Information 3t1i MRE11A crystal structure of human mre11: understanding tumorigenic mutations 3.0Å AUTH Y.B.PARK,J.CHAE,Y.KIM,Y.CHOTITL CRYSTAL STRUCTURE OF HUMAN MRE11: UNDERSTANDING TUMORIGENICTITL 2 MUTATIONSREF STRUCTURE V. 19 1591 2011REFN ISSN 0969-2126PMID 22078559DOI 10.1016/J.STR.2011.09.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3q8k FEN1 crystal structure of human flap endonuclease fen1 (wt) in complex with product 5-flap dna, sm3+, and k+ 2.2Å AUTH S.E.TSUTAKAWA,S.CLASSEN,B.R.CHAPADOS,A.S.ARVAI,L.D.FINGER,AUTH 2 G.GUENTHER,C.G.TOMLINSON,P.THOMPSON,A.H.SARKER,B.SHEN,AUTH 3 P.K.COOPER,J.A.GRASBY,J.A.TAINERTITL HUMAN FLAP ENDONUCLEASE STRUCTURES, DNA DOUBLE-BASETITL 2 FLIPPING, AND A UNIFIED UNDERSTANDING OF THE FEN1TITL 3 SUPERFAMILY.REF CELL(CAMBRIDGE,MASS.) V. 145 198 2011REFN ISSN 0092-8674PMID 21496641DOI 10.1016/J.CELL.2011.03.004 […]
General Structure Information 4awn DNASE1 structure of recombinant human dnase i (rhdnasei) in complex with magnesium and phosphate. 1.95Å AUTH G.PARSIEGLA,C.NOGUERE,L.SANTELL,R.A.LAZARUS,Y.BOURNETITL THE STRUCTURE OF HUMAN DNASE I BOUND TO MAGNESIUM ANDTITL 2 PHOSPHATE IONS POINTS TO A CATALYTIC MECHANISM COMMON TOTITL 3 MEMBERS OF THE DNASE I-LIKE SUPERFAMILY.REF BIOCHEMISTRY V. 51 10250 2012REFN ISSN 0006-2960PMID […]
General Structure Information 2c01 RNASE2 crystal structures of eosinophil-derived neurotoxin in complex with the inhibitors 5-atp, ap3a, ap4a and ap5a 1.24Å AUTH M.D.BAKER,D.E.HOLLOWAY,G.J.SWAMINATHAN,K.R.ACHARYATITL CRYSTAL STRUCTURES OF EOSINOPHIL-DERIVEDTITL 2 NEUROTOXIN (EDN) IN COMPLEX WITH THE INHIBITORSTITL 3 5- ATP, AP(3)A, AP(4)A, AND AP(5)A.REF BIOCHEMISTRY V. 45 416 2006REFN ISSN 0006-2960PMID 16401072DOI 10.1021/BI0518592 Variant Set Distributions Mapped […]
General Structure Information 2a1i ERCC1 crystal structure of the central domain of human ercc1 1.9Å AUTH O.V.TSODIKOV,J.H.ENZLIN,O.D.SCHARER,T.ELLENBERGERTITL CRYSTAL STRUCTURE AND DNA BINDING FUNCTIONS OFTITL 2 ERCC1, A SUBUNIT OF THE DNA STRUCTURE-SPECIFICTITL 3 ENDONUCLEASE XPF-ERCC1.REF PROC.NATL.ACAD.SCI.USA V. 102 11236 2005REFN ISSN 0027-8424PMID 16076955DOI 10.1073/PNAS.0504341102 Variant Set Distributions Mapped Variants