General Structure Information
| PDB ID | 2zix |
| HGNC Gene Label(s) | MUS81 |
| Structure Name | crystal structure of the mus81-eme1 complex |
| Resolution | 3.5Å |
| Reference | AUTH J.H.CHANG,J.J.KIM,J.M.CHOI,J.H.LEE,Y.CHOTITL CRYSTAL STRUCTURE OF THE MUS81-EME1 COMPLEXREF GENES DEV. V. 22 1093 2008REFN ISSN 0890-9369PMID 18413719DOI 10.1101/GAD.1618708 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 270 |
| Number Of SNVs | 87 |
| Number Of Permutations | 53445 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.074 |
| p-value | 0.246 |
COSMIC
| Number Of Residues | 270 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.498 |
| p-value | 0.726 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
