Assessment of Structural Intolerance and Durability
General Structure Information 3op5 VRK1 human vaccinia-related kinase 1 2.4Å AUTH C.K.ALLERSTON,S.UTTARKAR,P.SAVITSKY,J.M.ELKINS,AUTH 2 P.FILIPPAKOPOULOS,T.KROJER,P.RELLOS,O.FEDOROV,J.ESWARAN,AUTH 3 B.BRENNER,T.KEATES,S.DAS,O.KING,R.CHALK,G.BERRIDGE,AUTH 4 F.VON DELFT,O.GILEADI,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,AUTH 5 C.BOUNTRA,S.KNAPPTITL HUMAN VACCINIA-RELATED KINASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×52 PELO solution structures of the c-terminal domain of the human pelota homolog (cgi-17) -1.0Å AUTH N.NAMEKI,M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C-TERMINAL DOMAIN OFTITL 2 THE HUMAN PELOTA HOMOLOG (CGI-17)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z0v SH3GL3 crystal structure of bar domain of endophilin-iii 2.49Å AUTH K.MURAYAMA,M.KATO-MURAYAMA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF BAR DOMAIN OF ENDOPHILIN-IIIREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kpk MAGI1 magi-1 pdz1 -1.0Å AUTH S.CHARBONNIER,Y.NOMINE,J.RAMIREZ,K.LUCK,A.CHAPELLE,AUTH 2 R.H.STOTE,G.TRAVE,B.KIEFFER,R.A.ATKINSONTITL THE STRUCTURAL AND DYNAMIC RESPONSE OF MAGI-1 PDZ1 WITHTITL 2 NON-CANONICAL DOMAIN BOUNDARIES TO BINDING OF HUMANTITL 3 PAPILLOMAVIRUS (HPV) E6REF J.MOL.BIOL. 2011REFN ESSN 1089-8638PMID 21238461DOI 10.1016/J.JMB.2011.01.015 Variant Set Distributions Mapped Variants
General Structure Information 4jvh QKI structure of the star domain of quaking protein in complex with rna 3.5Å AUTH M.TEPLOVA,M.HAFNER,D.TEPLOV,K.ESSIG,T.TUSCHL,D.J.PATELTITL STRUCTURE-FUNCTION STUDIES OF STAR FAMILY QUAKING PROTEINSTITL 2 BOUND TO THEIR IN VIVO RNA TARGET SITES.REF GENES DEV. V. 27 928 2013REFN ISSN 0890-9369PMID 23630077DOI 10.1101/GAD.216531.113 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2a7o SETD2 solution structure of the hset2/hypb sri domain -1.0Å AUTH M.LI,H.P.PHATNANI,Z.GUAN,H.SAGE,A.GREENLEAF,P.ZHOUTITL SOLUTION STRUCTURE OF THE SET2 RPB1 INTERACTINGTITL 2 DOMAIN OF HUMAN SET2 AND ITS INTERACTION WITH THETITL 3 HYPERPHOSPHORYLATED C-TERMINAL DOMAIN OF RPB1REF PROC.NATL.ACAD.SCI.USA V. 102 17636 2005REFN ISSN 0027-8424PMID 16314571DOI 10.1073/PNAS.0506350102 Variant Set Distributions Mapped Variants
General Structure Information 2b9e NSUN5 human nsun5 protein 1.65Å AUTH J.R.MIN,H.WU,H.ZENG,P.LOPPNAU,M.SUNDSTROM,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN NSUN5 PROTEIN INTITL 2 COMPLEX WITH S-ADENOSYL-L-METHIONINEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wgl TOLLIP solution structure of cue domain in the c-terminal of human toll-interacting protein (tollip) -1.0Å AUTH C.ZHAO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF CUE DOMAIN IN THE C-TERMINALTITL 2 OF HUMAN TOLL-INTERACTING PROTEIN (TOLLIP)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2eq3 ZNF347 solution structure of the 17th c2h2 type zinc finger domain of zinc finger protein 347 -1.0Å AUTH K.FUTAMI,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 17TH C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 347REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmy STRBP solution structure of dsrm domain in spermatid perinuclear rna-bind protein -1.0Å AUTH S.KADIRVEL,F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,AUTH 2 T.TERADA,S.YOKOYAMATITL SOLUTION STRUCTURE OF DSRM DOMAIN IN SPERMATIDTITL 2 PERINUCLEAR RNA-BIND PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants