Assessment of Structural Intolerance and Durability
General Structure Information 1uw4 UPF3B the structural basis of the interaction between nonsense mediated decay factors upf2 and upf3 1.95Å AUTH J.KADLEC,E.IZAURRALDE,S.CUSACKTITL THE STRUCTURAL BASIS FOR THE INTERACTION BETWEENTITL 2 NONSENSE-MEDIATED MRNA DECAY FACTORS UPF2 AND UPF3REF NAT.STRUCT.MOL.BIOL. V. 11 330 2004REFN ISSN 1545-9993PMID 15004547DOI 10.1038/NSMB741 Variant Set Distributions Mapped Variants
General Structure Information 3rqf PDCD10 cerebral cavernous malformation 3 (ccm3) in complex with paxillin ld2 2.7Å AUTH X.LI,W.JI,R.ZHANG,E.FOLTA-STOGNIEW,W.MIN,T.J.BOGGONTITL MOLECULAR RECOGNITION OF LEUCINE-ASPARTATE REPEAT (LD)TITL 2 MOTIFS BY THE FOCAL ADHESION TARGETING HOMOLOGY DOMAIN OFTITL 3 CEREBRAL CAVERNOUS MALFORMATION 3 (CCM3).REF J.BIOL.CHEM. V. 286 26138 2011REFN ISSN 0021-9258PMID 21632544DOI 10.1074/JBC.M110.211250 Variant Set Distributions Mapped Variants
General Structure Information 4fqn CCM2 crystal structure of the ccm2 c-terminal harmonin homology domain (hhd) 1.9Å AUTH O.S.FISHER,R.ZHANG,X.LI,J.W.MURPHY,B.DEMELER,T.J.BOGGONTITL STRUCTURAL STUDIES OF CEREBRAL CAVERNOUS MALFORMATIONS 2TITL 2 (CCM2) REVEAL A FOLDED HELICAL DOMAIN AT ITS C-TERMINUS.REF FEBS LETT. V. 587 272 2013REFN ISSN 0014-5793PMID 23266514DOI 10.1016/J.FEBSLET.2012.12.011 Variant Set Distributions Mapped Variants
General Structure Information 2rt5 SPEN structural insights into the recruitment of smrt by the co-repressor sharp under phosphorylative regulation -1.0Å AUTH S.MIKAMI,T.KANABA,N.TAKIZAWA,A.KOBAYASHI,R.MAESAKI,AUTH 2 T.FUJIWARA,Y.ITO,M.MISHIMATITL STRUCTURAL INSIGHTS INTO THE RECRUITMENT OF SMRT BY THETITL 2 COREPRESSOR SHARP UNDER PHOSPHORYLATIVE REGULATIONREF STRUCTURE 2013REFN ISSN 0969-2126PMID 24268649DOI 10.1016/J.STR.2013.10.007 Variant Set Distributions Mapped Variants
General Structure Information 2lqt CHCHD7 solution structure of chchd7 -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,D.JAISWAL,S.NERI,AUTH 2 R.PERUZZINI,J.WINKELMANNTITL STRUCTURAL CHARACTERIZATION OF CHCHD5 AND CHCHD7: TWOTITL 2 ATYPICAL HUMAN TWIN CX(9)C PROTEINS.REF J.STRUCT.BIOL. V. 180 190 2012REFN ISSN 1047-8477PMID 22842048DOI 10.1016/J.JSB.2012.07.007 Variant Set Distributions Mapped Variants
General Structure Information 4frw PVRL4 crystal structure of human nectin-4 extracellular fragment d1-d2 3.5Å AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2efl FNBP1 crystal structure of the efc domain of formin-binding protein 17 2.61Å AUTH A.SHIMADA,H.NIWA,K.TSUJITA,S.SUETSUGU,K.NITTA,AUTH 2 K.HANAWA-SUETSUGU,R.AKASAKA,Y.NISHINO,M.TOYAMA,L.CHEN,AUTH 3 Z.-J.LIU,B.-C.WANG,M.YAMAMOTO,T.TERADA,A.MIYAZAWA,A.TANAKA,AUTH 4 S.SUGANO,M.SHIROUZU,K.NAGAYAMA,T.TAKENAWA,S.YOKOYAMATITL CURVED EFC/F-BAR-DOMAIN DIMERS ARE JOINED END TO END INTO ATITL 2 FILAMENT FOR MEMBRANE INVAGINATION IN ENDOCYTOSISREF CELL(CAMBRIDGE,MASS.) V. 129 761 2007REFN ISSN 0092-8674PMID 17512409DOI 10.1016/J.CELL.2007.03.040 Variant Set Distributions Ripley’s K […]
General Structure Information 3l0c CTDSP1 crystal structure of scp1 phosphatase d206a mutant with trapped inorganic phosphate 2.45Å AUTH M.ZHANG,J.LIU,Y.KIM,J.E.DIXON,S.L.PFAFF,G.N.GILL,J.P.NOEL,AUTH 2 Y.ZHANGTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE PHOSPHORYLTITL 2 TRANSFER REACTION MEDIATED BY THE HUMAN SMALL C-TERMINALTITL 3 DOMAIN PHOSPHATASE, SCP1.REF PROTEIN SCI. V. 19 974 2010REFN ISSN 0961-8368PMID 20222012DOI 10.1002/PRO.375 Variant Set Distributions Mapped […]
General Structure Information 3tg3 DUSP16 crystal structure of the mapk binding domain of mkp7 2.67Å AUTH Y.Y.ZHANG,J.W.WU,Z.X.WANGTITL A DISTINCT INTERACTION MODE REVEALED BY THE CRYSTALTITL 2 STRUCTURE OF THE KINASE P38ALPHA WITH THE MAPK BINDINGTITL 3 DOMAIN OF THE PHOSPHATASE MKP5.REF SCI.SIGNAL. V. 4 RA88 2011REFN ESSN 1937-9145PMID 22375048DOI 10.1126/SCISIGNAL.2002241 Variant Set Distributions Mapped Variants
General Structure Information 2db6 STAC3 solution structure of rsgi ruh-051, a c1 domain of stac3 from human cdna -1.0Å AUTH T.ABE,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,H.HIROTA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-051, A C1 DOMAIN OFTITL 2 STAC3 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants