Assessment of Structural Intolerance and Durability
General Structure Information 2e9x GINS4 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3g65 RAD9A crystal structure of the human rad9-rad1-hus1 dna damage checkpoint complex 2.9Å AUTH A.S.DORE,M.L.KILKENNY,N.J.RZECHORZEK,L.H.PEARLTITL CRYSTAL STRUCTURE OF THE RAD9-RAD1-HUS1 DNA DAMAGETITL 2 CHECKPOINT COMPLEX–IMPLICATIONS FOR CLAMP LOADING ANDTITL 3 REGULATION.REF MOL.CELL V. 34 735 2009REFN ISSN 1097-2765PMID 19446481DOI 10.1016/J.MOLCEL.2009.04.027 Variant Set Distributions Mapped Variants
General Structure Information 2dlk ZNF692 solution structure of the first and the second zf-c2h2 domains of zinc finger protein 692 -1.0Å AUTH H.P.ZHANG,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND THE SECONDTITL 2 ZF-C2H2 DOMAINS OF ZINC FINGER PROTEIN 692REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2din CDC5L solution structure of the myb_dna-binding domain of human cell division cycle 5-like protein -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE MYB_DNA-BINDING DOMAINTITL 2 OF HUMAN CELL DIVISION CYCLE 5-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4bhx PEG3 crystal structure of the scan domain from human paternally expressed gene 3 protein 1.95Å AUTH V.RIMSA,T.C.EADSFORTH,W.N.HUNTERTITL STRUCTURE OF THE SCAN DOMAIN OF HUMAN PATERNALLY EXPRESSEDTITL 2 GENE 3 PROTEIN.REF PLOS ONE V. 8E69538 2013REFN ISSN 1932-6203PMID 23936039DOI 10.1371/JOURNAL.PONE.0069538 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2aq0 ERCC4 solution structure of the human homodimeric dna repair protein xpf -1.0Å AUTH D.DAS,K.TRIPSIANES,N.G.JASPERS,J.H.HOEIJMAKERS,AUTH 2 R.KAPTEIN,R.BOELENS,G.FOLKERSTITL THE HHH DOMAIN OF THE HUMAN DNA REPAIR PROTEIN XPFTITL 2 FORMS STABLE HOMODIMERSREF PROTEINS V. 70 1551 2008REFN ISSN 0887-3585PMID 17912758DOI 10.1002/PROT.21635 Variant Set Distributions Mapped Variants
General Structure Information 2xnk TOPBP1 structure and function of the rad9-binding region of the dna damage checkpoint adaptor topbp1 2.6Å AUTH M.RAPPAS,A.W.OLIVER,L.H.PEARLTITL STRUCTURE AND FUNCTION OF THE RAD9-BINDING REGION OF THETITL 2 DNA-DAMAGE CHECKPOINT ADAPTOR TOPBP1.REF NUCLEIC ACIDS RES. V. 39 313 2011REFN ISSN 0305-1048PMID 20724438DOI 10.1093/NAR/GKQ743 Variant Set Distributions Mapped Variants
General Structure Information 1x6f ZNF462 solution structures of the c2h2 type zinc finger domain of human zinc finger protein 462 -1.0Å AUTH M.SATO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C2H2 TYPE ZINC FINGERTITL 2 DOMAIN OF HUMAN ZINC FINGER PROTEIN 462REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rnx KAT2B the structural basis for site-specific lysine-acetylated histone recognition by the bromodomains of the human transcriptional co-activators pcaf and cbp -1.0Å AUTH L.ZENG,Q.ZHANG,G.GERONA-NAVARRO,N.MOSHKINA,M.M.ZHOUTITL STRUCTURAL BASIS OF SITE-SPECIFIC HISTONETITL 2 RECOGNITION BY THE BROMODOMAINS OF HUMANTITL 3 COACTIVATORS PCAF AND CBP/P300REF STRUCTURE V. 16 643 2008REFN ISSN 0969-2126PMID 18400184DOI 10.1016/J.STR.2008.01.010 Variant Set […]
General Structure Information 3m66 MTERFD1 crystal structure of human mitochondrial transcription termination factor 3 1.6Å AUTH H.SPAHR,T.SAMUELSSON,B.M.HALLBERG,C.M.GUSTAFSSONTITL STRUCTURE OF MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTORTITL 2 3 REVEALS A NOVEL NUCLEIC ACID-BINDING DOMAIN.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 397 386 2010REFN ISSN 0006-291XPMID 20430012DOI 10.1016/J.BBRC.2010.04.130 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants