Assessment of Structural Intolerance and Durability
General Structure Information 3ljw PBRM1 crystal structure of the second bromodomain of human polybromo 1.5Å AUTH Z.CHARLOP-POWERS,L.ZENG,Q.ZHANG,M.M.ZHOUTITL STRUCTURAL INSIGHTS INTO SELECTIVE HISTONE H3 RECOGNITIONTITL 2 BY THE HUMAN POLYBROMO BROMODOMAIN 2.REF CELL RES. V. 20 529 2010REFN ISSN 1001-0602PMID 20368734DOI 10.1038/CR.2010.43 Variant Set Distributions Mapped Variants
General Structure Information 3g1n HUWE1 catalytic domain of the human e3 ubiquitin-protein ligase huwe1 2.6Å AUTH J.R.WALKER,L.QIU,Y.LI,T.DAVIS,W.TEMPEL,J.WEIGELT,AUTH 2 C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,AUTH 3 S.DHE-PAGANONTITL HECT DOMAIN OF HUMAN HUWE1/MULEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3av1 HIST2H3A the human nucleosome structure containing the histone variant h3.2 2.5Å AUTH H.TACHIWANA,A.OSAKABE,T.SHIGA,Y.MIYA,H.KIMURA,W.KAGAWA,AUTH 2 H.KURUMIZAKATITL STRUCTURES OF HUMAN NUCLEOSOMES CONTAINING MAJOR HISTONE H3TITL 2 VARIANTSREF ACTA CRYSTALLOGR.,SECT.D V. 67 578 2011REFN ISSN 0907-4449PMID 21636898DOI 10.1107/S0907444911014818 Variant Set Distributions Mapped Variants
General Structure Information 3av1 HIST2H3C the human nucleosome structure containing the histone variant h3.2 2.5Å AUTH H.TACHIWANA,A.OSAKABE,T.SHIGA,Y.MIYA,H.KIMURA,W.KAGAWA,AUTH 2 H.KURUMIZAKATITL STRUCTURES OF HUMAN NUCLEOSOMES CONTAINING MAJOR HISTONE H3TITL 2 VARIANTSREF ACTA CRYSTALLOGR.,SECT.D V. 67 578 2011REFN ISSN 0907-4449PMID 21636898DOI 10.1107/S0907444911014818 Variant Set Distributions Mapped Variants
General Structure Information 3av1 HIST2H3D the human nucleosome structure containing the histone variant h3.2 2.5Å AUTH H.TACHIWANA,A.OSAKABE,T.SHIGA,Y.MIYA,H.KIMURA,W.KAGAWA,AUTH 2 H.KURUMIZAKATITL STRUCTURES OF HUMAN NUCLEOSOMES CONTAINING MAJOR HISTONE H3TITL 2 VARIANTSREF ACTA CRYSTALLOGR.,SECT.D V. 67 578 2011REFN ISSN 0907-4449PMID 21636898DOI 10.1107/S0907444911014818 Variant Set Distributions Mapped Variants
General Structure Information 3bo5 SETMAR crystal structure of methyltransferase domain of human histone-lysine n-methyltransferase setmar 1.59Å AUTH H.WU,V.V.LUNIN,H.REN,E.DOBROVETSKY,J.WEIGELT,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,J.MIN,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMANTITL 2 HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR IN COMPLEX WITHTITL 3 ADOHCY.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1wgx MIS18BP1 solution structure of rsgi ruh-022, a myb dna-binding domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-022, A MYBTITL 2 DNA-BINDING DOMAIN IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3b6y IFI16 crystal structure of the second hin-200 domain of interferon-inducible protein 16 2.35Å AUTH J.C.C.LIAO,R.LAM,M.RAVICHANDRAN,S.DUAN,W.TEMPEL,AUTH 2 N.Y.CHIRGADZE,C.H.ARROWSMITHTITL CRYSTAL STRUCTURE ANALYSIS OF THE SECOND HIN DOMAIN OFTITL 2 IFI16.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3i7p DCAF12 crystal structure of ddb1 in complex with the h-box motif of wdr40a 3.0Å AUTH T.LI,E.I.ROBERT,P.C.VAN BREUGEL,M.STRUBIN,N.ZHENGTITL A PROMISCUOUS ALPHA-HELICAL MOTIF ANCHORS VIRALTITL 2 HIJACKERS AND SUBSTRATE RECEPTORS TO THE CUL4-DDB1TITL 3 UBIQUITIN LIGASE MACHINERY.REF NAT.STRUCT.MOL.BIOL. V. 17 105 2010REFN ISSN 1545-9993PMID 19966799DOI 10.1038/NSMB.1719 Variant Set Distributions Mapped Variants
General Structure Information 3a6n HIST3H3 the nucleosome containing a testis-specific histone variant, human h3t 2.7Å AUTH H.TACHIWANA,W.KAGAWA,A.OSAKABE,K.KAWAGUCHI,T.SHIGA,AUTH 2 Y.HAYASHI-TAKANAKA,H.KIMURA,H.KURUMIZAKATITL STRUCTURAL BASIS OF INSTABILITY OF THE NUCLEOSOME CONTAININGTITL 2 A TESTIS-SPECIFIC HISTONE VARIANT, HUMAN H3TREF PROC.NATL.ACAD.SCI.USA V. 107 10454 2010REFN ISSN 0027-8424PMID 20498094DOI 10.1073/PNAS.1003064107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]