General Structure Information 2ja3 CLCN5 cytoplasmic domain of the human chloride transporter clc-5 in complex with adp 3.05Å AUTH S.MEYER,S.SAVARESI,I.C.FORSTER,R.DUTZLERTITL NUCLEOTIDE RECOGNITION BY THE CYTOPLASMIC DOMAINTITL 2 OF THE HUMAN CHLORIDE TRANSPORTER CLC-5REF NAT.STRUCT.MOL.BIOL. V. 14 60 2006REFN ISSN 1545-9993PMID 17195847DOI 10.1038/NSMB1188 Variant Set Distributions Mapped Variants
General Structure Information 3ii6 LIG4 structure of human xrcc4 in complex with the tandem brct domains of dna ligaseiv. 2.4Å AUTH P.Y.WU,P.FRIT,S.MEESALA,S.DAUVILLIER,M.MODESTI,AUTH 2 S.N.ANDRES,Y.HUANG,J.SEKIGUCHI,P.CALSOU,B.SALLES,AUTH 3 M.S.JUNOPTITL STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN THETITL 2 HUMAN DNA REPAIR PROTEINS DNA LIGASE IV AND XRCC4REF MOL.CELL.BIOL. V. 11 3163 2009REFN ISSN 0270-7306PMID 19332554 Variant Set Distributions Ripley’s K […]
General Structure Information 2rd0 PIK3CA structure of a human p110alpha/p85alpha complex 3.05Å AUTH C.H.HUANG,D.MANDELKER,O.SCHMIDT-KITTLER,Y.SAMUELS,AUTH 2 V.E.VELCULESCU,K.W.KINZLER,B.VOGELSTEIN,S.B.GABELLI,AUTH 3 L.M.AMZELTITL THE STRUCTURE OF A HUMAN P110ALPHA/P85ALPHA COMPLEXTITL 2 ELUCIDATES THE EFFECTS OF ONCOGENIC PI3KALPHA MUTATIONS.REF SCIENCE V. 318 1744 2007REFN ISSN 0036-8075PMID 18079394DOI 10.1126/SCIENCE.1150799 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dwb ECE1 structure of human ece-1 complexed with phosphoramidon 2.38Å AUTH H.SCHULZ,G.E.DALE,Y.KARIMI-NEJAD,C.OEFNERTITL STRUCTURE OF HUMAN ENDOTHELIN-CONVERTING ENZYME I COMPLEXEDTITL 2 WITH PHOSPHORAMIDONREF J.MOL.BIOL. V. 385 178 2009REFN ISSN 0022-2836PMID 18992253DOI 10.1016/J.JMB.2008.10.052 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2zt7 GARS crystal structure of human glycyl-trna synthetase (glyrs) in complex with glycine and atp 2.7Å AUTH R.T.GUO,Y.E.CHONG,M.GUO,X.L.YANGTITL CRYSTAL STRUCTURES AND BIOCHEMICAL ANALYSES SUGGESTTITL 2 UNIQUE MECHANISM AND ROLE FOR HUMAN GLYRS IN AP4ATITL 3 HOMEOSTASISREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3evs GDF5 crystal structure of the gdf-5:bmp receptor ib complex. 2.1Å AUTH A.KOTZSCH,J.NICKEL,A.SEHER,W.SEBALD,T.D.MULLERTITL CRYSTAL STRUCTURE ANALYSIS REVEALS A SPRING-LOADED LATCH ASTITL 2 MOLECULAR MECHANISM FOR GDF-5-TYPE I RECEPTOR SPECIFICITY.REF EMBO J. V. 28 937 2009REFN ISSN 0261-4189PMID 19229295DOI 10.1038/EMBOJ.2009.37 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2w86 FBN1 crystal structure of fibrillin-1 domains cbegf9hyb2cbegf10, calcium saturated form 1.8Å AUTH S.A.JENSEN,S.IQBAL,E.D.LOWE,C.REDFIELD,P.A.HANDFORDTITL STRUCTURE AND INTERDOMAIN INTERACTIONS OF A HYBRIDTITL 2 DOMAIN: A DISULPHIDE-RICH MODULE OF THETITL 3 FIBRILLIN/LTBP SUPERFAMILY OF MATRIX PROTEINS.REF STRUCTURE V. 17 759 2009REFN ISSN 0969-2126PMID 19446531DOI 10.1016/J.STR.2009.03.014 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jif ACADSB structure of human short-branched chain acyl-coa dehydrogenase (acadsb) 2.0Å AUTH A.C.W.PIKE,V.HOZJAN,C.SMEE,F.H.NIESEN,K.L.KAVANAGH,C.UMEANO,AUTH 2 A.P.TURNBULL,F.VON DELFT,J.WEIGELT,A.EDWARDS,C.H.ARROWSMITH,AUTH 3 M.SUNDSTROM,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SHORT-BRANCHED CHAIN ACYL-COATITL 2 DEHYDROGENASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3e0g LIFR structure of the leukemia inhibitory factor receptor (lif-r) domains d1-d5 3.1Å AUTH G.SKINIOTIS,P.J.LUPARDUS,M.MARTICK,T.WALZ,K.C.GARCIATITL STRUCTURAL ORGANIZATION OF A FULL-LENGTH GP130/LIF-RTITL 2 CYTOKINE RECEPTOR TRANSMEMBRANE COMPLEX.REF MOL.CELL V. 31 737 2008REFN ISSN 1097-2765PMID 18775332DOI 10.1016/J.MOLCEL.2008.08.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3isq HPD crystal structure of human 4-hydroxyphenylpyruvate dioxygenase 1.75Å AUTH E.S.PILKA,N.SHAFQAT,R.COCKING,J.E.BRAY,T.KROJER,A.C.W.PIKE,AUTH 2 F.VON DELFT,W.W.YUE,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,AUTH 3 C.BOUNTRA,U.OPPERMANN,K.L.KAVANAGHTITL CRYSTAL STRUCTURE OF HUMAN 4-HYDROXYPHENYLPYRUVATETITL 2 DIOXYGENASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants