General Structure Information 3kv4 PHF8 structure of phf8 in complex with histone h3 2.19Å AUTH J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,AUTH 2 X.CHENGTITL ENZYMATIC AND STRUCTURAL INSIGHTS FOR SUBSTRATETITL 2 SPECIFICITY OF A FAMILY OF JUMONJI HISTONE LYSINETITL 3 DEMETHYLASES.REF NAT.STRUCT.MOL.BIOL. V. 17 38 2010REFN ISSN 1545-9993PMID 20023638DOI 10.1038/NSMB.1753 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4ie5 FTO crystal structure of the human fat mass and obesity associated protein (fto) in complex with n-[(3-hydroxypyridin-2-yl)carbonyl]glycine (md6) 1.95Å AUTH W.S.AIK,M.DEMETRIADES,M.K.K.HAMDAN,E.A.L.BAGG,K.K.YEOH,AUTH 2 C.LEJEUNE,Z.ZHANG,M.A.MCDONOUGH,C.J.SCHOFIELDTITL STRUCTURAL BASIS FOR INHIBITION OF THE FAT MASS AND OBESITYTITL 2 ASSOCIATED PROTEIN (FTO)REF J.MED.CHEM. V. 56 3680 2013REFN ISSN 0022-2623PMID 23547775DOI 10.1021/JM400193D Variant Set Distributions Mapped Variants
General Structure Information 2iuw ALKBH3 crystal structure of human abh3 in complex with iron ion and 2-oxoglutarate 1.5Å AUTH O.SUNDHEIM,C.B.VAGBO,M.BJORAS,M.M.L.DESOUSA,AUTH 2 V.TALSTAD,P.A.AAS,F.DRABLOS,H.E.KROKAN,J.A.TAINER,AUTH 3 G.SLUPPHAUGTITL HUMAN ABH3 STRUCTURE AND KEY RESIDUES FORTITL 2 OXIDATIVE DEMETHYLATION TO REVERSE DNA/RNA DAMAGE.REF EMBO J. V. 25 3389 2006REFN ISSN 0261-4189PMID 16858410DOI 10.1038/SJ.EMBOJ.7601219 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3uyj KDM8 crystal structure of jmjd5 catalytic core domain in complex with nickle and alpha-kg 2.35Å AUTH X.SU,H.LITITL CRYSTAL STRUCTURE OF JMJD5 CATALYTIC CORE DOMAIN IN COMPLEXTITL 2 WITH NICKLE AND ALPHA-KGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kv4 H3F3C structure of phf8 in complex with histone h3 2.19Å AUTH J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,AUTH 2 X.CHENGTITL ENZYMATIC AND STRUCTURAL INSIGHTS FOR SUBSTRATETITL 2 SPECIFICITY OF A FAMILY OF JUMONJI HISTONE LYSINETITL 3 DEMETHYLASES.REF NAT.STRUCT.MOL.BIOL. V. 17 38 2010REFN ISSN 1545-9993PMID 20023638DOI 10.1038/NSMB.1753 Variant Set Distributions Mapped Variants
General Structure Information 4nj4 ALKBH5 crystal structure of human alkbh5 2.02Å AUTH W.AIK,J.S.SCOTTI,H.CHOI,L.GONG,M.DEMETRIADES,C.J.SCHOFIELD,AUTH 2 M.A.MCDONOUGHTITL STRUCTURE OF HUMAN RNA N6-METHYLADENINE DEMETHYLASE ALKBH5TITL 2 PROVIDES INSIGHTS INTO ITS MECHANISMS OF NUCLEIC ACIDTITL 3 RECOGNITION AND DEMETHYLATION.REF NUCLEIC ACIDS RES. V. 42 4741 2014REFN ISSN 0305-1048PMID 24489119DOI 10.1093/NAR/GKU085 Variant Set Distributions Mapped Variants
General Structure Information 3kv5 KDM7A structure of kiaa1718, human jumonji demethylase, in complex with n-oxalylglycine 2.39Å AUTH J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,AUTH 2 X.CHENGTITL ENZYMATIC AND STRUCTURAL INSIGHTS FOR SUBSTRATETITL 2 SPECIFICITY OF A FAMILY OF JUMONJI HISTONE LYSINETITL 3 DEMETHYLASES.REF NAT.STRUCT.MOL.BIOL. V. 17 38 2010REFN ISSN 1545-9993PMID 20023638DOI 10.1038/NSMB.1753 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4hon KDM4D crystal structure of human jmjd2d/kdm4d in complex with an h3k9me3 peptide and 2-oxoglutarate 1.8Å AUTH S.KRISHNAN,R.C.TRIEVELTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF JMJD2D REVEALSTITL 2 MOLECULAR BASIS FOR SITE-SPECIFIC DEMETHYLATION AMONG JMJD2TITL 3 DEMETHYLASES.REF STRUCTURE V. 21 98 2013REFN ISSN 0969-2126PMID 23219879DOI 10.1016/J.STR.2012.10.018 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2ox0 KDM4A crystal structure of jmjd2a complexed with histone h3 peptide dimethylated at lys9 1.95Å AUTH S.S.NG,K.L.KAVANAGH,M.A.MCDONOUGH,D.BUTLER,E.S.PILKA,AUTH 2 B.M.LIENARD,J.E.BRAY,P.SAVITSKY,O.GILEADI,F.VON DELFT,AUTH 3 N.R.ROSE,J.OFFER,J.C.SCHEINOST,T.BOROWSKI,M.SUNDSTROM,AUTH 4 C.J.SCHOFIELD,U.OPPERMANNTITL CRYSTAL STRUCTURES OF HISTONE DEMETHYLASE JMJD2A REVEALTITL 2 BASIS FOR SUBSTRATE SPECIFICITY.REF NATURE V. 448 87 2007REFN ISSN 0028-0836PMID 17589501DOI 10.1038/NATURE05971 Variant Set Distributions Mapped Variants