Assessment of Structural Intolerance and Durability
General Structure Information 3dof ARL2 complex of arl2 and bart, crystal form 2 3.3Å AUTH T.ZHANG,S.LI,Y.ZHANG,C.ZHONG,Z.LAI,J.DINGTITL CRYSTAL STRUCTURE OF THE ARL2-GTP-BART COMPLEXTITL 2 REVEALS A NOVEL RECOGNITION AND BINDING MODE OFTITL 3 SMALL GTPASE WITH EFFECTORREF STRUCTURE V. 17 602 2009REFN ISSN 0969-2126PMID 19368893DOI 10.1016/J.STR.2009.01.014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3ihp USP5 covalent ubiquitin-usp5 complex 2.8Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 A.BOCHKAREV,S.DHE-PAGANONTITL COVALENT UBIQUITIN-USP5 COMPLEXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2k7p FLNA filamin a ig-like domains 16-17 -1.0Å AUTH O.K.HEIKKINEN,S.RUSKAMO,P.V.KONAREV,D.I.SVERGUN,AUTH 2 T.IIVANAINEN,S.M.HEIKKINEN,P.PERMI,H.KOSKELA,AUTH 3 I.KILPELAINEN,J.YLANNETITL ATOMIC STRUCTURES OF TWO NOVEL IMMUNOGLOBULIN-LIKETITL 2 DOMAIN PAIRS IN THE ACTIN CROSS-LINKING PROTEINTITL 3 FILAMINREF J.BIOL.CHEM. V. 284 25450 2009REFN ISSN 0021-9258PMID 19622754DOI 10.1074/JBC.M109.019661 Variant Set Distributions Mapped Variants
General Structure Information 3cnk FLNA crystal structure of the dimerization domain of human filamin a 1.65Å AUTH M.-D.SEO,S.-H.SEOK,H.IM,A.-R.KWON,S.-J.LEE,AUTH 2 H.-R.KIM,Y.CHO,D.PARK,B.-J.LEETITL CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAIN OFTITL 2 HUMAN FILAMIN AREF PROTEINS V. 75 258 2008REFN ISSN 0887-3585PMID 19137608DOI 10.1002/PROT.22336 Variant Set Distributions Mapped Variants
General Structure Information 2k3t FLNA solution structure of ig-like domain 23 from human filamin a -1.0Å AUTH F.NAKAMURA,O.HEIKKINEN,O.T.PENTIKAINEN,T.M.OSBORN,AUTH 2 K.E.KASZA,D.A.WEITZ,O.KUPIAINEN,P.PERMI,AUTH 3 I.KILPELAINEN,J.YLANNE,J.H.HARTWIG,T.P.STOSSELTITL MOLECULAR BASIS OF FILAMIN A-FILGAP INTERACTIONTITL 2 AND ITS IMPAIRMENT IN CONGENITAL DISORDERSTITL 3 ASSOCIATED WITH FILAMIN A MUTATIONSREF PLOS ONE V. 4 E4928 2009REFN ESSN 1932-6203PMID 19293932DOI 10.1371/JOURNAL.PONE.0004928 Variant Set Distributions Mapped […]
General Structure Information 2wfn FLNA filamin a actin binding domain 3.2Å AUTH S.RUSKAMO,J.YLANNETITL STRUCTURE OF THE HUMAN FILAMIN A ACTIN-BINDING DOMAINREF ACTA CRYSTALLOGR.,SECT.D V. 65 1217 2009REFN ISSN 0907-4449PMID 19923718DOI 10.1107/S0907444909037330 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2zv6 SERPINB3 crystal structure of human squamous cell carcinoma antigen 1 2.7Å AUTH B.ZHENG,Y.MATOBA,T.KUMAGAI,C.KATAGIRI,T.HIBINO,AUTH 2 M.SUGIYAMATITL CRYSTAL STRUCTURE OF SCCA1 AND INSIGHT ABOUT THETITL 2 INTERACTION WITH JNK1REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 380 143 2009REFN ISSN 0006-291XPMID 19166818DOI 10.1016/J.BBRC.2009.01.057 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2wax DDX6 structure of the human ddx6 c-terminal domain in complex with an edc3-fdf peptide 2.3Å AUTH F.TRITSCHLER,J.E.BRAUN,A.EULALIO,V.TRUFFAULT,AUTH 2 E.IZAURRALDE,O.WEICHENRIEDERTITL STRUCTURAL BASIS FOR THE MUTUALLY EXCLUSIVETITL 2 ANCHORING OF P BODY COMPONENTS EDC3 AND TRAL TOTITL 3 THE DEAD BOX PROTEIN DDX6/ME31B.REF MOL.CELL V. 33 661 2009REFN ISSN 1097-2765PMID 19285948DOI 10.1016/J.MOLCEL.2009.02.014 Variant […]
General Structure Information 3ebm TPT1 crystal structure of human translationally controlled tumour associated protein (htctp) mutant e12v 2.6Å AUTH X.DONG,B.YANG,Y.LI,C.ZHONG,J.DINGTITL MOLECULAR BASIS OF THE ACCELERATION OF THE GDP-GTPTITL 2 EXCHANGE OF HUMAN RAS HOMOLOG ENRICHED IN BRAIN BYTITL 3 HUMAN TRANSLATIONALLY CONTROLLED TUMOR PROTEIN.REF J.BIOL.CHEM. V. 284 23754 2009REFN ISSN 0021-9258PMID 19570981DOI 10.1074/JBC.M109.012823 Variant Set […]
General Structure Information 3d3l ALOX12 the 2.6 a crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12s-type (casp target) 2.6Å AUTH L.TRESAUGUES,M.MOCHE,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 R.D.BUSAM,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 M.D.HERMAN,A.JOHANSSON,I.JOHANSSON,A.KALLAS,AUTH 5 T.KARLBERG,T.KOTENYOVA,L.LEHTIO,M.E.NILSSON,AUTH 6 T.NYMAN,K.OLESEN,C.PERSSON,J.SAGEMARK,H.SCHUELER,AUTH 7 L.SVENSSON,A.G.THORSELL,S.VAN DEN BERG,M.WELIN,AUTH 8 J.WEIGELT,M.WIKSTROM,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE LIPOXYGENASE DOMAIN OFTITL 2 HUMAN ARACHIDONATE 12-LIPOXYGENASE, 12S-TYPE.REF TO BE PUBLISHEDREFN […]