General Structure Information
| PDB ID | 2zv6 |
| HGNC Gene Label(s) | SERPINB3 |
| Structure Name | crystal structure of human squamous cell carcinoma antigen 1 |
| Resolution | 2.7Å |
| Reference | AUTH B.ZHENG,Y.MATOBA,T.KUMAGAI,C.KATAGIRI,T.HIBINO,AUTH 2 M.SUGIYAMATITL CRYSTAL STRUCTURE OF SCCA1 AND INSIGHT ABOUT THETITL 2 INTERACTION WITH JNK1REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 380 143 2009REFN ISSN 0006-291XPMID 19166818DOI 10.1016/J.BBRC.2009.01.057 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 350 |
| Number Of SNVs | 82 |
| Number Of Permutations | 38120 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.697 |
COSMIC
| Number Of Residues | 350 |
| Number Of SNVs | 12 |
| Number Of Permutations | 3910 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.061 |
| p-value | 0.999 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 82 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | -0.023 |
| p-value | 0.943 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
