Assessment of Structural Intolerance and Durability
General Structure Information 2d2z CLIC4 crystal structure of soluble form of clic4 2.2Å AUTH Y.F.LI,D.F.LI,Z.H.ZENG,D.C.WANGTITL TRIMERIC STRUCTURE OF THE WILD SOLUBLE CHLORIDETITL 2 INTRACELLULAR ION CHANNEL CLIC4 OBSERVED INTITL 3 CRYSTALSREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 343 1272 2006REFN ISSN 0006-291XPMID 16581025DOI 10.1016/J.BBRC.2006.03.099 Variant Set Distributions Mapped Variants
General Structure Information 2boa CPA4 human procarboxypeptidase a4. 2.2Å AUTH R.GARCIA-CASTELLANOS,R.BONET-FIGUEREDO,I.PALLARES,AUTH 2 S.VENTURA,F.X.AVILES,J.VENDRELL,F.X.GOMIS-RUTHTITL DETAILED MOLECULAR COMPARISON BETWEEN THETITL 2 INHIBITION MODE OF A/B-TYPE CARBOXYPEPTIDASES INTITL 3 THE ZYMOGEN STATE AND BY THE ENDOGENOUS INHIBITORTITL 4 LATEXIN.REF CELL.MOL.LIFE SCI. V. 62 1996 2005REFN ISSN 1420-682XPMID 16091843DOI 10.1007/S00018-005-5174-4 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1zvd SMURF2 regulation of smurf2 ubiquitin ligase activity by anchoring the e2 to the hect domain 2.1Å AUTH A.A.OGUNJIMI,D.J.BRIANT,N.PECE-BARBARA,C.LE ROY,AUTH 2 G.M.DI GUGLIELMO,P.KAVSAK,R.K.RASMUSSEN,B.T.SEET,F.SICHERI,AUTH 3 J.L.WRANATITL REGULATION OF SMURF2 UBIQUITIN LIGASE ACTIVITY BY ANCHORINGTITL 2 THE E2 TO THE HECT DOMAIN.REF MOL.CELL V. 19 297 2005REFN ISSN 1097-2765PMID 16061177DOI 10.1016/J.MOLCEL.2005.06.028 Variant Set Distributions […]
General Structure Information 3iwp CUTC crystal structure of human copper homeostasis protein cutc 2.5Å AUTH Y.LI,J.DU,P.ZHANG,J.DINGTITL CRYSTAL STRUCTURE OF HUMAN COPPER HOMEOSTASISTITL 2 PROTEIN CUTC REVEALS A POTENTIAL COPPER-BINDINGTITL 3 SITEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3eay SENP7 crystal structure of the human senp7 catalytic domain 2.4Å AUTH C.D.LIMA,D.REVERTERTITL STRUCTURE OF THE HUMAN SENP7 CATALYTIC DOMAIN ANDTITL 2 POLY-SUMO DECONJUGATION ACTIVITIES FOR SENP6 ANDTITL 3 SENP7.REF J.BIOL.CHEM. V. 283 32045 2008REFN ISSN 0021-9258PMID 18799455DOI 10.1074/JBC.M805655200 Variant Set Distributions Mapped Variants
General Structure Information 2bo9 LXN human carboxypeptidase a4 in complex with human latexin. 1.6Å AUTH I.PALLARES,R.BONET,R.GARCIA-CASTELLANOS,S.VENTURA,AUTH 2 F.X.AVILES,J.VENDRELL,F.X.GOMIS-RUETHTITL STRUCTURE OF HUMAN CARBOXYPEPTIDASE A4 WITH ITSTITL 2 ENDOGENOUS PROTEIN INHIBITOR, LATEXIN.REF PROC.NATL.ACAD.SCI.USA V. 102 3978 2005REFN ISSN 0027-8424PMID 15738388DOI 10.1073/PNAS.0500678102 Variant Set Distributions Mapped Variants
General Structure Information 1twq PGLYRP3 crystal structure of the c-terminal pgn-binding domain of human pgrp- ialpha in complex with pgn analog muramyl tripeptide 2.3Å AUTH R.GUAN,A.ROYCHOWDHURY,B.EMBER,S.KUMAR,G.-A.BOONS,AUTH 2 R.A.MARIUZZATITL STRUCTURAL BASIS FOR PEPTIDOGLYCAN BINDING BY PEPTIDOGLYCANTITL 2 RECOGNITION PROTEINSREF PROC.NATL.ACAD.SCI.USA V. 101 17168 2004REFN ISSN 0027-8424PMID 15572450DOI 10.1073/PNAS.0407856101 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3cfv RBBP7 structural basis of the interaction of rbap46/rbap48 with histone h4 2.6Å AUTH N.V.MURZINA,X.Y.PEI,W.ZHANG,M.SPARKES,AUTH 2 J.VICENTE-GARCIA,J.V.PRATAP,S.H.MCLAUGHLIN,AUTH 3 T.R.BEN-SHAHAR,A.VERREAULT,B.F.LUISI,E.D.LAUETITL STRUCTURAL BASIS FOR THE RECOGNITION OF HISTONE H4TITL 2 BY THE HISTONE-CHAPERONE RBAP46.REF STRUCTURE V. 16 1077 2008REFN ISSN 0969-2126PMID 18571423DOI 10.1016/J.STR.2008.05.006 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 1q1u FGF12 crystal structure of human fhf1b (fgf12b) 1.7Å AUTH S.K.OLSEN,M.GARBI,N.ZAMPIERI,A.V.ELISEENKOVA,AUTH 2 D.M.ORNITZ,M.GOLDFARB,M.MOHAMMADITITL FIBROBLAST GROWTH FACTOR (FGF) HOMOLOGOUS FACTORSTITL 2 SHARE STRUCTURAL BUT NOT FUNCTIONAL HOMOLOGY WITHTITL 3 FGFSREF J.BIOL.CHEM. V. 278 34226 2003REFN ISSN 0021-9258PMID 12815063DOI 10.1074/JBC.M303183200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1q1u FGF12 crystal structure of human fhf1b (fgf12b) 1.7Å AUTH S.K.OLSEN,M.GARBI,N.ZAMPIERI,A.V.ELISEENKOVA,AUTH 2 D.M.ORNITZ,M.GOLDFARB,M.MOHAMMADITITL FIBROBLAST GROWTH FACTOR (FGF) HOMOLOGOUS FACTORSTITL 2 SHARE STRUCTURAL BUT NOT FUNCTIONAL HOMOLOGY WITHTITL 3 FGFSREF J.BIOL.CHEM. V. 278 34226 2003REFN ISSN 0021-9258PMID 12815063DOI 10.1074/JBC.M303183200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]