General Structure Information
| PDB ID | 1q1u |
| HGNC Gene Label(s) | FGF12 |
| Structure Name | crystal structure of human fhf1b (fgf12b) |
| Resolution | 1.7Å |
| Reference | AUTH S.K.OLSEN,M.GARBI,N.ZAMPIERI,A.V.ELISEENKOVA,AUTH 2 D.M.ORNITZ,M.GOLDFARB,M.MOHAMMADITITL FIBROBLAST GROWTH FACTOR (FGF) HOMOLOGOUS FACTORSTITL 2 SHARE STRUCTURAL BUT NOT FUNCTIONAL HOMOLOGY WITHTITL 3 FGFSREF J.BIOL.CHEM. V. 278 34226 2003REFN ISSN 0021-9258PMID 12815063DOI 10.1074/JBC.M303183200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 138 |
| Number Of SNVs | 16 |
| Number Of Permutations | 1523 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.05 |
| p-value | 0.815 |
COSMIC
| Number Of Residues | 138 |
| Number Of SNVs | 6 |
| Number Of Permutations | 947 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.067 |
| p-value | 0.18 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.267 |
| p-value | 0.404 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
