Assessment of Structural Intolerance and Durability
General Structure Information 2j4o TAB1 structure of tab1 2.25Å AUTH S.H.CONNER,G.KULAR,M.PEGGIE,S.SHEPHERD,AUTH 2 A.W.SCHUTTELKOPF,P.COHEN,D.M.F.VAN AALTENTITL TAK1-BINDING PROTEIN 1 IS A PSEUDOPHOSPHATASE.REF BIOCHEM.J. V. 399 427 2006REFN ISSN 0264-6021PMID 16879102DOI 10.1042/BJ20061077 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2rei EPHA7 kinase domain of human ephrin type-a receptor 7 (epha7) 1.6Å AUTH J.R.WALKER,D.CUERRIER,C.BUTLER-COLE,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL KINASE DOMAIN OF HUMAN EPHRIN TYPE-A RECEPTOR 7TITL 2 (EPHA7).REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2d7m FLNC solution structure of the 14th filamin domain from human filamin c -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 14TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2azt GNMT crystal structure of h176n mutant of human glycine n-methyltransferase 2.7Å AUTH Z.LUKA,S.PAKHOMOVA,Y.LUKA,M.E.NEWCOMER,C.WAGNERTITL DESTABILIZATION OF HUMAN GLYCINE N-METHYLTRANSFERASE BYTITL 2 H176N MUTATION.REF PROTEIN SCI. V. 16 1957 2007REFN ISSN 0961-8368PMID 17660255DOI 10.1110/PS.072921507 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2wfj PPIG atomic resolution crystal structure of the ppiase domain of human cyclophilin g in complex with cyclosporin a. 0.75Å AUTH C.M.STEGMANN,D.SEELIGER,G.M.SHELDRICK,B.L.DE GROOT,M.C.WAHLTITL THE THERMODYNAMIC INFLUENCE OF TRAPPED WATER MOLECULES ON ATITL 2 PROTEIN-LIGAND INTERACTION.REF ANGEW.CHEM.INT.ED.ENGL. V. 48 5207 2009REFN ISSN 1433-7851PMID 19499554DOI 10.1002/ANIE.200900481 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2v7o CAMK2G crystal structure of human calcium-calmodulin-dependent protein kinase ii gamma 2.25Å AUTH P.RELLOS,A.C.W.PIKE,F.H.NIESEN,E.SALAH,W.H.LEE,AUTH 2 F.VON DELFT,S.KNAPPTITL STRUCTURE OF THE CAMKIIDELTA/CALMODULIN COMPLEXTITL 2 REVEALS THE MOLECULAR MECHANISM OF CAMKII KINASETITL 3 ACTIVATION.REF PLOS BIOL. V. 8 426 2010REFN ISSN 1544-9173PMID 20668654DOI 10.1371/JOURNAL.PBIO.1000426 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4epu ANGPT1 ang1 fibrinogen-related domain (fred) 2.1Å AUTH C.C.YEYKAL,L.SUNDARESAN,M.MRKSICH,E.J.ADAMSTITL BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF THE ANG1TITL 2 FIBRINOGEN-RELATED DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2dll IRF4 solution structure of the irf domain of human interferon regulator factors 4 -1.0Å AUTH H.P.ZHANG,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IRF DOMAIN OF HUMANTITL 2 INTERFERON REGULATOR FACTORS 4REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2y05 PTGR1 crystal structure of human leukotriene b4 12-hydroxydehydrogenase in complex with nadp and raloxifene 2.2Å AUTH W.W.YUE,N.SHAFQAT,T.KROJER,A.C.W.PIKE,F.VON DELFT,R.SETHI,AUTH 2 P.SAVITSKY,C.JOHANSSON,C.ARROWSMITH,J.WEIGELT,A.EDWARDS,AUTH 3 C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE B4TITL 2 12-HYDROXYDEHYDROGENASE IN COMPLEX WITH NADP AND RALOXIFENEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3o0z ROCK1 crystal structure of a coiled-coil domain from human rock i 2.33Å AUTH D.TU,Y.LI,H.K.SONG,A.V.TOMS,C.J.GOULD,S.B.FICARRO,J.A.MARTO,AUTH 2 B.L.GOODE,M.J.ECKTITL CRYSTAL STRUCTURE OF A COILED-COIL DOMAIN FROM HUMAN ROCK I.REF PLOS ONE V. 6 E1808 2011REFN ESSN 1932-6203PMID 21445309DOI 10.1371/JOURNAL.PONE.0018080 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants