2DLL.A | IRF4

General Structure Information

PDB ID 2dll
HGNC Gene Label(s) IRF4
Structure Name solution structure of the irf domain of human interferon regulator factors 4
Resolution -1.0Å
Reference AUTH H.P.ZHANG,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IRF DOMAIN OF HUMANTITL 2 INTERFERON REGULATOR FACTORS 4REF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 108
Number Of SNVs 10
Number Of Permutations 928
Optimal Distance Threshold 8.0
K Statistic 0.133
p-value 0.344
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 10
Number Of COSMIC SNVs 3
Optimal Distance Threshold 6.0
K Statistic 0.289
p-value 0.306

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants