Assessment of Structural Intolerance and Durability
General Structure Information 4m6w FANCM crystal structure of the c-terminal segment of fancm in complex with faap24 2.9Å AUTH H.YANG,T.ZHANG,Y.TAO,F.WANG,L.TONG,J.DINGTITL STRUCTURAL INSIGHTS INTO THE FUNCTIONS OF THE FANCM-FAAP24TITL 2 COMPLEX IN DNA REPAIR.REF NUCLEIC ACIDS RES. V. 41 10573 2013REFN ISSN 0305-1048PMID 24003026DOI 10.1093/NAR/GKT788 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 1u5d SKAP1 crystal structure of the ph domain of skap55 1.7Å AUTH Y.TANG,K.D.SWANSON,B.G.NEEL,M.J.ECKTITL STRUCTURAL BASIS FOR THE DIMERIZATION ANDTITL 2 PHOSPHOINOSITIDE SPECIFICITY OF THE SRCTITL 3 KINASE-ASSOCIATED PHOSPHOPROTEINS SKAP55 ANDTITL 4 SKAP-HOMREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2c2n MCAT structure of human mitochondrial malonyltransferase 1.55Å AUTH G.BUNKOCZI,S.MISQUITTA,X.WU,W.H.LEE,A.ROJKOVA,G.KOCHAN,AUTH 2 K.L.KAVANAGH,U.OPPERMANN,S.SMITHTITL STRUCTURAL BASIS FOR DIFFERENT SPECIFICITIES OFTITL 2 ACYLTRANSFERASES ASSOCIATED WITH THE HUMAN CYTOSOLIC ANDTITL 3 MITOCHONDRIAL FATTY ACID SYNTHASES.REF CHEM.BIOL. V. 16 667 2009REFN ISSN 1074-5521PMID 19549604DOI 10.1016/J.CHEMBIOL.2009.04.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cry KIRREL3 solution structure of the fifth ig-like domain of human kin of irre like 3 -1.0Å AUTH C.KUROSAKI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAIN OFTITL 2 HUMAN KIN OF IRRE LIKE 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3u1k PNPT1 crystal structure of human pnpase 2.13Å AUTH C.L.LIN,Y.-T.WANG,W.-Z.YANG,Y.-Y.HSIAO,H.S.YUANTITL CRYSTAL STRUCTURE OF HUMAN POLYNUCLEOTIDE PHOSPHORYLASE:TITL 2 INSIGHTS INTO ITS DOMAIN FUNCTION IN RNA BINDING ANDTITL 3 DEGRADATIONREF NUCLEIC ACIDS RES. V. 40 4146 2012REFN ISSN 0305-1048PMID 22210891DOI 10.1093/NAR/GKR1281 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3s4e DUSP19 crystal structrue of a novel mitogen-activated protein kinase phosphatase, skrp1 1.26Å AUTH C.H.WEI,S.Y.RYU,Y.H.JEON,M.Y.YOON,D.G.JEONG,S.J.KIM,S.E.RYUTITL CRYSTAL STRUCTURE OF A NOVEL MITOGEN-ACTIVATED PROTEINTITL 2 KINASE PHOSPHATASE, SKRP1.REF PROTEINS V. 79 3242 2011REFN ISSN 0887-3585PMID 21989941DOI 10.1002/PROT.23156 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3hhc IFNL3 interferon-lambda is functionally an interferon but structurally related to the il-10 family 2.8Å AUTH H.H.GAD,C.DELLGREN,O.J.HAMMING,S.VENDS,S.R.PALUDAN,AUTH 2 R.HARTMANNTITL INTERFERON-{LAMBDA} IS FUNCTIONALLY AN INTERFERONTITL 2 BUT STRUCTURALLY RELATED TO THE INTERLEUKIN-10TITL 3 FAMILYREF J.BIOL.CHEM. V. 284 20869 2009REFN ISSN 0021-9258PMID 19457860DOI 10.1074/JBC.M109.002923 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1va9 DSCAML1 solution structure of the second fniii domain of dscaml1 protein -1.0Å AUTH X.-R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FNIII DOMAIN OFTITL 2 DSCAML1 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4if8 SERPINA12 structure of vaspin 2.08Å AUTH J.T.HEIKER,N.KLOTING,P.KOVACS,E.B.KUETTNER,N.STRATER,AUTH 2 S.SCHULTZ,M.KERN,M.STUMVOLL,M.BLUHER,A.G.BECK-SICKINGERTITL VASPIN INHIBITS KALLIKREIN 7 BY SERPIN MECHANISMREF CELL.MOL.LIFE SCI. V. 70 2569 2013REFN ISSN 1420-682XPMID 23370777DOI 10.1007/S00018-013-1258-8 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4lev MB21D1 structure of human cgas 1.95Å AUTH X.LI,C.SHU,G.YI,C.T.CHATON,C.L.SHELTON,J.DIAO,X.ZUO,C.C.KAO,AUTH 2 A.B.HERR,P.LITITL CYCLIC GMP-AMP SYNTHASE IS ACTIVATED BY DOUBLE-STRANDEDTITL 2 DNA-INDUCED OLIGOMERIZATION.REF IMMUNITY V. 39 1019 2013REFN ISSN 1074-7613PMID 24332030DOI 10.1016/J.IMMUNI.2013.10.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants