General Structure Information
| PDB ID | 2c2n |
| HGNC Gene Label(s) | MCAT |
| Structure Name | structure of human mitochondrial malonyltransferase |
| Resolution | 1.55Å |
| Reference | AUTH G.BUNKOCZI,S.MISQUITTA,X.WU,W.H.LEE,A.ROJKOVA,G.KOCHAN,AUTH 2 K.L.KAVANAGH,U.OPPERMANN,S.SMITHTITL STRUCTURAL BASIS FOR DIFFERENT SPECIFICITIES OFTITL 2 ACYLTRANSFERASES ASSOCIATED WITH THE HUMAN CYTOSOLIC ANDTITL 3 MITOCHONDRIAL FATTY ACID SYNTHASES.REF CHEM.BIOL. V. 16 667 2009REFN ISSN 1074-5521PMID 19549604DOI 10.1016/J.CHEMBIOL.2009.04.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 316 |
| Number Of SNVs | 98 |
| Number Of Permutations | 42819 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.093 |
| p-value | 0.366 |
COSMIC
| Number Of Residues | 316 |
| Number Of SNVs | 4 |
| Number Of Permutations | 140 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.367 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 98 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.141 |
| p-value | 0.372 |