Assessment of Structural Intolerance and Durability
General Structure Information 1dc2 CDKN2A solution nmr structure of tumor suppressor p16ink4a, 20 structures -1.0Å AUTH C.YUAN,T.L.SELBY,J.LI,I.J.BYEON,M.D.TSAITITL TUMOR SUPPRESSOR INK4: REFINEMENT OF P16INK4ATITL 2 STRUCTURE AND DETERMINATION OF P15INK4B STRUCTURETITL 3 BY COMPARATIVE MODELING AND NMR DATA.REF PROTEIN SCI. V. 9 1120 2000REFN ISSN 0961-8368PMID 10892805 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2ed9 DCC solution structure of the third fibronectin type iii domain of human netrin receptor dcc -1.0Å AUTH N.TOCHIO,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN NETRIN RECEPTOR DCCREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3dof ARL2 complex of arl2 and bart, crystal form 2 3.3Å AUTH T.ZHANG,S.LI,Y.ZHANG,C.ZHONG,Z.LAI,J.DINGTITL CRYSTAL STRUCTURE OF THE ARL2-GTP-BART COMPLEXTITL 2 REVEALS A NOVEL RECOGNITION AND BINDING MODE OFTITL 3 SMALL GTPASE WITH EFFECTORREF STRUCTURE V. 17 602 2009REFN ISSN 0969-2126PMID 19368893DOI 10.1016/J.STR.2009.01.014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1ej5 WAS solution structure of the autoinhibited conformation of wasp -1.0Å AUTH A.S.KIM,L.T.KAKALIS,N.ABDUL-MANAN,G.A.LIU,M.K.ROSENTITL AUTOINHIBITION AND ACTIVATION MECHANISMS OF THETITL 2 WISKOTT-ALDRICH SYNDROME PROTEIN.REF NATURE V. 404 151 2000REFN ISSN 0028-0836PMID 10724160DOI 10.1038/35010088 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3cog CTH crystal structure of human cystathionase (cystathionine gamma lyase) in complex with dl-propargylglycine 2.0Å AUTH Q.SUN,R.COLLINS,S.HUANG,L.HOLMBERG-SCHIAVONE,G.S.ANAND,AUTH 2 C.H.TAN,S.VAN-DEN-BERG,L.W.DENG,P.K.MOORE,T.KARLBERG,AUTH 3 J.SIVARAMANTITL STRUCTURAL BASIS FOR THE INHIBITION MECHANISM OF HUMANTITL 2 CYSTATHIONINE GAMMA-LYASE, AN ENZYME RESPONSIBLE FOR THETITL 3 PRODUCTION OF H(2)S.REF J.BIOL.CHEM. V. 284 3076 2009REFN ISSN 0021-9258PMID 19019829DOI 10.1074/JBC.M805459200 Variant Set […]
General Structure Information 3fxm PPM1A crystal structure of human protein phosphatase 1a (ppm1a) bound with citrate at 10 mm of mn2+ 2.5Å AUTH T.HU,L.WANG,K.WANG,J.CHEN,H.JIANG,X.SHENTITL STRUCTURAL BASIS FOR THE MN2+-DEPENDENT ACTIVATIONTITL 2 OF HUMAN PPM1AREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1ncn CD86 the receptor-binding domain of human b7-2 2.7Å AUTH X.ZHANG,J.D.SCHWARTZ,S.C.ALMO,S.G.NATHENSONTITL CRYSTAL STRUCTURE OF THE RECEPTOR-BINDING DOMAINTITL 2 OF HUMAN B7-2: INSIGHTS INTO ORGANIZATION ANDTITL 3 SIGNALINGREF PROC.NATL.ACAD.SCI.USA V. 100 2586 2003REFN ISSN 0027-8424PMID 12606712DOI 10.1073/PNAS.252771499 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3ihp USP5 covalent ubiquitin-usp5 complex 2.8Å AUTH J.R.WALKER,G.V.AVVAKUMOV,S.XUE,C.BUTLER-COLE,AUTH 2 J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 3 A.BOCHKAREV,S.DHE-PAGANONTITL COVALENT UBIQUITIN-USP5 COMPLEXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3n2z PRCP the structure of human prolylcarboxypeptidase at 2.80 angstroms resolution 2.79Å AUTH S.M.SOISSON,S.B.PATEL,P.D.ABEYWICKREMA,N.J.BRYNE,R.E.DIEHL,AUTH 2 D.L.HALL,R.E.FORD,J.C.REID,K.W.RICKERT,J.M.SHIPMAN,S.SHARMA,AUTH 3 K.J.LUMBTITL STRUCTURAL DEFINITION AND SUBSTRATE SPECIFICITY OF THE S28TITL 2 PROTEASE FAMILY: THE CRYSTAL STRUCTURE OF HUMANTITL 3 PROLYLCARBOXYPEPTIDASE.REF BMC STRUCT.BIOL. V. 10 16 2010REFN ESSN 1472-6807PMID 20540760DOI 10.1186/1472-6807-10-16 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 4b3f IGHMBP2 crystal structure of 1ghmbp2 helicase 2.5Å AUTH S.C.LIM,M.W.BOWLER,T.F.LAI,H.SONGTITL THE IGHMBP2 HELICASE STRUCTURE REVEALS THE MOLECULAR BASISTITL 2 FOR DISEASE-CAUSING MUTATIONS IN DMSA1.REF NUCLEIC ACIDS RES. V. 40 11009 2012REFN ISSN 0305-1048PMID 22965130DOI 10.1093/NAR/GKS792 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants