Assessment of Structural Intolerance and Durability
General Structure Information 2obh XPC centrin-xpc peptide 1.8Å AUTH J.B.CHARBONNIER,E.RENAUD,S.MIRON,M.H.LE DU,Y.BLOUQUIT,AUTH 2 P.DUCHAMBON,P.CHRISTOVA,A.SHOSHEVA,T.ROSE,J.F.ANGULO,AUTH 3 C.T.CRAESCUTITL STRUCTURAL, THERMODYNAMIC, AND CELLULAR CHARACTERIZATION OFTITL 2 HUMAN CENTRIN 2 INTERACTION WITH XERODERMA PIGMENTOSUM GROUPTITL 3 C PROTEIN.REF J.MOL.BIOL. V. 373 1032 2007REFN ISSN 0022-2836PMID 17897675DOI 10.1016/J.JMB.2007.08.046 Variant Set Distributions Mapped Variants
General Structure Information 3vw9 GLO1 human glyoxalase i with an n-hydroxypyridone inhibitor 1.47Å AUTH T.CHIBA,J.OHWADA,H.SAKAMOTO,T.KOBAYASHI,T.A.FUKAMI,M.IRIE,AUTH 2 T.MIURA,K.OHARA,H.KOYANOTITL DESIGN AND EVALUATION OF AZAINDOLE-SUBSTITUTEDTITL 2 N-HYDROXYPYRIDONES AS GLYOXALASE I INHIBITORSREF BIOORG.MED.CHEM.LETT. V. 22 7486 2012REFN ISSN 0960-894XPMID 23122816DOI 10.1016/J.BMCL.2012.10.045 Variant Set Distributions Mapped Variants
General Structure Information 4hot IFIT5 crystal structure of full-length human ifit5 with 5`-triphosphate oligoadenine 2.5Å AUTH Y.M.ABBAS,A.PICHLMAIR,M.W.GORNA,G.SUPERTI-FURGA,B.NAGARTITL STRUCTURAL BASIS FOR VIRAL 5-PPP-RNA RECOGNITION BY HUMANTITL 2 IFIT PROTEINS.REF NATURE V. 494 60 2013REFN ISSN 0028-0836PMID 23334420DOI 10.1038/NATURE11783 Variant Set Distributions Mapped Variants
General Structure Information 4ag4 DDR1 crystal structure of a ddr1-fab complex 2.8Å AUTH F.CARAFOLI,M.C.MAYER,K.SHIRAISHI,M.A.PECHEVA,L.Y.CHAN,R.NAN,AUTH 2 B.LEITINGER,E.HOHENESTERTITL STRUCTURE OF THE DISCOIDIN DOMAIN RECEPTOR 1 EXTRACELLULARTITL 2 REGION BOUND TO AN INHIBITORY FAB FRAGMENT REVEALS FEATURESTITL 3 IMPORTANT FOR SIGNALING.REF STRUCTURE V. 20 688 2012REFN ISSN 0969-2126PMID 22483115DOI 10.1016/J.STR.2012.02.011 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1nlw MXD1 crystal structure of mad-max recognizing dna 2.0Å AUTH S.K.NAIR,S.K.BURLEYTITL X-RAY STRUCTURES OF MYC-MAX AND MAD-MAXTITL 2 RECOGNIZING DNA: MOLECULAR BASES OF REGULATION BYTITL 3 PROTO-ONCOGENIC TRANSCRIPTION FACTORSREF CELL(CAMBRIDGE,MASS.) V. 112 193 2003REFN ISSN 0092-8674PMID 12553908DOI 10.1016/S0092-8674(02)01284-9 Variant Set Distributions Mapped Variants
General Structure Information 3cyy TJP1 the crystal structure of zo-1 pdz2 in complex with the cx43 peptide 2.4Å AUTH J.CHEN,L.PAN,Z.WEI,Y.ZHAO,M.ZHANGTITL DOMAIN-SWAPPED DIMERIZATION OF ZO-1 PDZ2 GENERATES SPECIFICTITL 2 AND REGULATORY CONNEXIN43-BINDING SITESREF EMBO J. V. 27 2113 2008REFN ISSN 0261-4189PMID 18636092DOI 10.1038/EMBOJ.2008.138 Variant Set Distributions Mapped Variants
General Structure Information 4h9q H3F3A complex structure 4 of daxx(e225a)/h3.3(sub5)/h4 1.95Å AUTH S.J.ELSASSER,H.HUANG,P.W.LEWIS,J.W.CHIN,D.C.ALLIS,D.J.PATELTITL DAXX CHAPERONE ENVELOPS AN H3.3/H4 DIMER DICTATINGTITL 2 H3.3-SPECIFIC READ OUTREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4h9q H3F3B complex structure 4 of daxx(e225a)/h3.3(sub5)/h4 1.95Å AUTH S.J.ELSASSER,H.HUANG,P.W.LEWIS,J.W.CHIN,D.C.ALLIS,D.J.PATELTITL DAXX CHAPERONE ENVELOPS AN H3.3/H4 DIMER DICTATINGTITL 2 H3.3-SPECIFIC READ OUTREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3o34 HIST1H3H crystal structure of trim24 phd-bromo complexed with h3(13-32)k23ac peptide 1.9Å AUTH W.W.TSAI,Z.WANG,T.T.YIU,K.C.AKDEMIR,W.XIA,S.WINTER,C.Y.TSAI,AUTH 2 X.SHI,D.SCHWARZER,W.PLUNKETT,B.ARONOW,O.GOZANI,W.FISCHLE,AUTH 3 M.C.HUNG,D.J.PATEL,M.C.BARTONTITL TRIM24 LINKS A NON-CANONICAL HISTONE SIGNATURE TO BREASTTITL 2 CANCER.REF NATURE V. 468 927 2010REFN ISSN 0028-0836PMID 21164480DOI 10.1038/NATURE09542 Variant Set Distributions Mapped Variants
General Structure Information 3o34 HIST1H3J crystal structure of trim24 phd-bromo complexed with h3(13-32)k23ac peptide 1.9Å AUTH W.W.TSAI,Z.WANG,T.T.YIU,K.C.AKDEMIR,W.XIA,S.WINTER,C.Y.TSAI,AUTH 2 X.SHI,D.SCHWARZER,W.PLUNKETT,B.ARONOW,O.GOZANI,W.FISCHLE,AUTH 3 M.C.HUNG,D.J.PATEL,M.C.BARTONTITL TRIM24 LINKS A NON-CANONICAL HISTONE SIGNATURE TO BREASTTITL 2 CANCER.REF NATURE V. 468 927 2010REFN ISSN 0028-0836PMID 21164480DOI 10.1038/NATURE09542 Variant Set Distributions Mapped Variants