Assessment of Structural Intolerance and Durability
General Structure Information 2r2j ERP44 crystal structure of human erp44 2.6Å AUTH L.K.WANG,L.WANG,S.VAVASSORI,S.J.LI,H.KE,T.ANELLI,M.DEGANO,AUTH 2 R.RONZONI,R.SITIA,F.SUN,C.C.WANGTITL CRYSTAL STRUCTURE OF HUMAN ERP44 SHOWS A DYNAMIC FUNCTIONALTITL 2 MODULATION BY ITS CARBOXY-TERMINAL TAIL.REF EMBO REP. 2008REFN ESSN 1469-3178PMID 18552768DOI 10.1038/EMBOR.2008.88 Variant Set Distributions Mapped Variants
General Structure Information 2z5e PSMG3 crystal structure of proteasome assembling chaperone 3 2.0Å AUTH H.YASHIRODA,T.MIZUSHIMA,K.OKAMOTO,T.KAMEYAMA,AUTH 2 H.HAYASHI,T.KISHIMOTO,S.NIWA,M.KASAHARA,E.KURIMOTO,AUTH 3 E.SAKATA,K.TAKAGI,A.SUZUKI,Y.HIRANO,S.MURATA,AUTH 4 K.KATO,T.YAMANE,K.TANAKATITL CRYSTAL STRUCTURE OF A CHAPERONE COMPLEX THATTITL 2 CONTRIBUTES TO THE ASSEMBLY OF YEAST 20STITL 3 PROTEASOMESREF NAT.STRUCT.MOL.BIOL. V. 15 228 2008REFN ISSN 1545-9993PMID 18278057DOI 10.1038/NSMB.1386 Variant Set Distributions Mapped Variants
General Structure Information 3fzm BAG1 crystal structures of hsc70/bag1 in complex with small molecule inhibitors 2.3Å AUTH D.S.WILLIAMSON,J.BORGOGNONI,A.CLAY,Z.DANIELS,AUTH 2 P.DOKURNO,M.J.DRYSDALE,N.FOLOPPE,G.L.FRANCIS,AUTH 3 C.J.GRAHAM,R.HOWES,A.T.MACIAS,J.B.MURRAY,R.PARSONS,AUTH 4 T.SHAW,A.E.SURGENOR,L.TERRY,Y.WANG,M.WOOD,AUTH 5 A.J.MASSEYTITL NOVEL ADENOSINE-DERIVED INHIBITORS OF 70 KDA HEATTITL 2 SHOCK PROTEIN, DISCOVERED THROUGH STRUCTURE-BASEDTITL 3 DESIGNREF J.MED.CHEM. V. 52 1510 2009REFN ISSN 0022-2623PMID 19256508DOI 10.1021/JM801627A Variant Set Distributions Ripley’s K […]
General Structure Information 2ctt DNAJA3 solution structure of zinc finger domain from human dnaj subfamily a menber 3 -1.0Å AUTH N.KOBAYASHI,N.TOCHIO,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF ZINC FINGER DOMAIN FROMTITL 2 HUMAN DNAJ SUBFAMILY A MENBER 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmx DNAJB8 solution structure of the j domain of dnaj homolog subfamily b member 8 -1.0Å AUTH S.OHNISHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE J DOMAIN OF DNAJ HOMOLOGTITL 2 SUBFAMILY B MEMBER 8REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bvo HSCB crystal structure of human co-chaperone protein hscb 3.0Å AUTH E.BITTO,C.A.BINGMAN,L.BITTOVA,D.A.KONDRASHOV,R.M.BANNEN,AUTH 2 B.G.FOX,J.L.MARKLEY,G.N.PHILLIPSTITL STRUCTURE OF HUMAN J-TYPE CO-CHAPERONE HSCB REVEALS ATITL 2 TETRACYSTEINE METAL-BINDING DOMAIN.REF J.BIOL.CHEM. V. 283 30184 2008REFN ISSN 0021-9258PMID 18713742DOI 10.1074/JBC.M804746200 Variant Set Distributions Mapped Variants
General Structure Information 3t30 NPM2 human nucleoplasmin (npm2): a histone chaperone in oocytes and early embryos 1.9Å AUTH O.PLATONOVA,I.V.AKEY,J.F.HEAD,C.W.AKEYTITL CRYSTAL STRUCTURE AND FUNCTION OF HUMAN NUCLEOPLASMINTITL 2 (NPM2): A HISTONE CHAPERONE IN OOCYTES AND EMBRYOS.REF BIOCHEMISTRY V. 50 8078 2011REFN ISSN 0006-2960PMID 21863821DOI 10.1021/BI2006652 Variant Set Distributions Mapped Variants
General Structure Information 1us7 CDC37 complex of hsp90 and p50 2.3Å AUTH S.M.ROE,M.M.U.ALI,P.MEYER,C.K.VAUGHAN,B.PANARETOU,P.W.PIPER,AUTH 2 C.PRODROMOU,L.H.PEARLTITL THE MECHANISM OF HSP90 REGULATION BY THE PROTEINTITL 2 KINASE-SPECIFIC COCHAPERONE P50(CDC37)REF CELL(CAMBRIDGE,MASS.) V. 116 87 2004REFN ISSN 0092-8674PMID 14718169DOI 10.1016/S0092-8674(03)01027-4 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2l3l TBCC the solution structure of the n-terminal domain of human tubulin binding cofactor c reveals a platform for the interaction with ab- tubulin -1.0Å AUTH M.F.GARCIA-MAYORAL,R.CASTANO,M.L.LOPEZ-FANARRAGA,J.C.ZABALA,AUTH 2 M.RICO,M.BRUIXTITL THE SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMANTITL 2 TUBULIN BINDING COFACTOR C REVEALS A PLATFORM FOR TUBULINTITL 3 INTERACTIONREF TO BE […]
General Structure Information 2yuh TBCC solution structure of the c-terminal region in human tubulin folding cofactor c -1.0Å AUTH K.SAITO,N.TOCHIO,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL REGION INTITL 2 HUMAN TUBULIN FOLDING COFACTOR CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants