Assessment of Structural Intolerance and Durability
General Structure Information 3qor NUDC crystal structure of human nuclear migration protein nudc 1.75Å AUTH M.ZHENG,T.CIERPICKI,A.J.BURDETTE,D.UTEPBERGENOV,P.L.JANCZYK,AUTH 2 U.DEREWENDA,P.T.STUKENBERG,K.A.CALDWELL,Z.S.DEREWENDATITL STRUCTURAL FEATURES AND CHAPERONE ACTIVITY OF THE NUDCTITL 2 PROTEIN FAMILY.REF J.MOL.BIOL. V. 409 722 2011REFN ISSN 0022-2836PMID 21530541DOI 10.1016/J.JMB.2011.04.018 Variant Set Distributions Mapped Variants
General Structure Information 3ebb PLAA plap/p97 complex 1.9Å AUTH L.QIU,N.PASHKOVA,J.R.WALKER,S.WINISTORFER,A.ALLALI-HASSANI,AUTH 2 M.AKUTSU,R.PIPER,S.DHE-PAGANONTITL STRUCTURE AND FUNCTION OF THE PLAA/UFD3-P97/CDC48 COMPLEX.REF J.BIOL.CHEM. V. 285 365 2010REFN ISSN 0021-9258PMID 19887378DOI 10.1074/JBC.M109.044685 Variant Set Distributions Mapped Variants
General Structure Information 2i32 ASF1A structure of a human asf1a-hira complex and insights into specificity of histone chaperone complex assembly 2.7Å AUTH Y.TANG,M.V.POUSTOVOITOV,K.ZHAO,M.GARFINKEL,AUTH 2 A.CANUTESCU,R.DUNBRACK,P.D.ADAMS,R.MARMORSTEINTITL STRUCTURE OF A HUMAN ASF1A-HIRA COMPLEX ANDTITL 2 INSIGHTS INTO SPECIFICITY OF HISTONE CHAPERONETITL 3 COMPLEX ASSEMBLY.REF NAT.STRUCT.MOL.BIOL. V. 13 921 2006REFN ISSN 1545-9993PMID 16980972DOI 10.1038/NSMB1147 Variant Set Distributions Mapped […]
General Structure Information 3o10 SACS crystal structure of the hepn domain from human sacsin 1.9Å AUTH G.KOZLOV,A.Y.DENISOV,M.GIRARD,M.J.DICAIRE,J.HAMLIN,AUTH 2 P.S.MCPHERSON,B.BRAIS,K.GEHRINGTITL STRUCTURAL BASIS OF DEFECTS IN THE SACSIN HEPN DOMAINTITL 2 RESPONSIBLE FOR AUTOSOMAL RECESSIVE SPASTIC ATAXIA OFTITL 3 CHARLEVOIX-SAGUENAY (ARSACS).REF J.BIOL.CHEM. V. 286 20407 2011REFN ISSN 0021-9258PMID 21507954DOI 10.1074/JBC.M111.232884 Variant Set Distributions Mapped Variants
General Structure Information 2ctr DNAJB9 solution structure of j-domain from human dnaj subfamily b menber 9 -1.0Å AUTH N.KOBAYASHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF J-DOMAIN FROM HUMAN DNAJTITL 2 SUBFAMILY B MENBER 9REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d9d BAG5 solution structure of the bag domain (275-350) of bag-family molecular chaperone regulator-5 -1.0Å AUTH A.ARAKAWA,N.HANDA,N.OHSAWA,M.SHIDA,T.KIGAWA,AUTH 2 F.HAYASHI,M.SHIROUZU,S.YOKOYAMATITL THE C-TERMINAL BAG DOMAIN OF BAG5 INDUCESTITL 2 CONFORMATIONAL CHANGES OF THE HSP70TITL 3 NUCLEOTIDE-BINDING DOMAIN FOR ADP-ATP EXCHANGEREF STRUCTURE V. 18 309 2010REFN ISSN 0969-2126PMID 20223214DOI 10.1016/J.STR.2010.01.004 Variant Set Distributions Mapped Variants
General Structure Information 1w0b AHSP solution structure of the human alpha-hemoglobin stabilizing protein (ahsp) p30a mutant -1.0Å AUTH C.M.SANTIVERI,J.M.PEREZ-CANADILLAS,M.K.VADIVELU,AUTH 2 M.D.ALLEN,T.J.RUTHERFORD,N.A.WATKINS,M.BYCROFTTITL NMR STRUCTURE OF THE ALPHA-HEMOGLOBIN CHAPERONETITL 2 AHSP: INSIGHTS INTO CONFORMATIONAL HETEROGENEITYTITL 3 AND BINDINGREF J.BIOL.CHEM. V. 279 34963 2004REFN ISSN 0021-9258PMID 15178680DOI 10.1074/JBC.M405016200 Variant Set Distributions Mapped Variants
General Structure Information 1xqr HSPBP1 crystal structure of the hspbp1 core domain 2.1Å AUTH Y.SHOMURA,Z.DRAGOVIC,H.C.CHANG,N.TZVETKOV,AUTH 2 J.C.YOUNG,J.L.BRODSKY,V.GUERRIERO,F.U.HARTL,AUTH 3 A.BRACHERTITL REGULATION OF HSP70 FUNCTION BY HSPBP1; STRUCTURALTITL 2 ANALYSIS REVEALS AN ALTERNATE MECHANISM FOR HSP70TITL 3 NUCLEOTIDE EXCHANGEREF MOL.CELL V. 17 367 2005REFN ISSN 1097-2765PMID 15694338DOI 10.1016/J.MOLCEL.2004.12.023 Variant Set Distributions Mapped Variants
General Structure Information 4h9p DAXX complex structure 3 of daxx/h3.3(sub5,g90a)/h4 2.2Å AUTH S.J.ELSASSER,H.HUANG,P.W.LEWIS,J.W.CHIN,D.C.ALLIS,D.J.PATELTITL DAXX CHAPERONE ENVELOPS AN H3.3/H4 DIMER DICTATINGTITL 2 H3.3-SPECIFIC READ OUTREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3cz9 PARK7 crystal structure of e18l dj-1 1.15Å AUTH A.C.WITT,M.LAKSHMINARASIMHAN,B.C.REMINGTON,S.HASIM,AUTH 2 E.POZHARSKI,M.A.WILSONTITL CYSTEINE PKA DEPRESSION BY A PROTONATED GLUTAMICTITL 2 ACID IN HUMAN DJ-1.REF BIOCHEMISTRY V. 47 7430 2008REFN ISSN 0006-2960PMID 18570440DOI 10.1021/BI800282D Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants