Assessment of Structural Intolerance and Durability
General Structure Information 3n1q CDON crystal structure of dhhn bound to cdofn3 2.89Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Mapped Variants
General Structure Information 3sqd PAXIP1 crystal structure of human ptip brct5/6-gamma h2ax complex 2.15Å AUTH W.YAN,Z.H.SHAOTITL CRYSTAL STRUCTURE OF HUMAN PTIP BRCT5/6-GAMMA H2AXREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3fga SGOL1 structural basis of pp2a and sgo interaction 2.7Å AUTH Z.XU,B.CETIN,M.ANGER,U.S.CHO,W.HELMHART,K.NASMYTH,W.XUTITL STRUCTURE AND FUNCTION OF THE PP2A-SHUGOSHIN INTERACTIONREF MOL.CELL V. 35 426 2009REFN ISSN 1097-2765PMID 19716788DOI 10.1016/J.MOLCEL.2009.06.031 Variant Set Distributions Mapped Variants
General Structure Information 3soo L1TD1 crystal structure of a line-1 type transposase domain-containing protein 1 (l1td1) from homo sapiens at 2.73 a resolution 2.73Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR STEM CELL BIOLOGY (STEMCELL)TITL CRYSTAL STRUCTURE OF A LINE-1 TYPE TRANSPOSASETITL 2 DOMAIN-CONTAINING PROTEIN 1 (L1TD1) FROM HOMO SAPIENS ATTITL 3 […]
General Structure Information 4bq7 RGMB crystal structure of the rgmb-neo1 complex form 2 6.6Å AUTH C.H.BELL,E.HEALEY,S.VAN ERP,B.BISHOP,C.TANG,R.J.C.GILBERT,AUTH 2 A.R.ARICESCU,R.J.PASTERKAMP,C.SIEBOLDTITL STRUCTURE OF THE REPULSIVE GUIDANCE MOLECULE (RGM)-NEOGENINTITL 2 SIGNALING HUBREF SCIENCE V. 341 77 2013REFN ISSN 0036-8075PMID 23744777DOI 10.1126/SCIENCE.1232322 Variant Set Distributions Mapped Variants
General Structure Information 3iai CA9 crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase ix 2.2Å AUTH V.ALTERIO,M.HILVO,A.DI FIORE,C.T.SUPURAN,P.PAN,S.PARKKILA,AUTH 2 A.SCALONI,J.PASTOREK,S.PASTOREKOVA,C.PEDONE,A.SCOZZAFAVA,AUTH 3 S.M.MONTI,G.DE SIMONETITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THETITL 2 TUMOR-ASSOCIATED HUMAN CARBONIC ANHYDRASE IX.REF PROC.NATL.ACAD.SCI.USA V. 106 16233 2009REFN ISSN 0027-8424PMID 19805286DOI 10.1073/PNAS.0908301106 Variant Set Distributions Mapped Variants
General Structure Information 3vpp CLEC9A crystal structure of the human clec9a c-type lectin-like domain 1.64Å AUTH J.G.ZHANG,P.E.CZABOTAR,A.N.POLICHENI,I.CAMINSCHI,S.S.WAN,AUTH 2 S.KITSOULIS,K.M.TULLETT,A.Y.ROBIN,R.BRAMMANANTH,AUTH 3 M.F.VAN DELFT,J.LU,L.A.OREILLY,E.C.JOSEFSSON,B.T.KILE,AUTH 4 W.J.CHIN,J.D.MINTERN,M.A.OLSHINA,W.WONG,J.BAUM,M.D.WRIGHT,AUTH 5 D.C.HUANG,N.MOHANDAS,R.L.COPPEL,P.M.COLMAN,N.A.NICOLA,AUTH 6 K.SHORTMAN,M.H.LAHOUDTITL THE DENDRITIC CELL RECEPTOR CLEC9A BINDS DAMAGED CELLS VIATITL 2 EXPOSED ACTIN FILAMENTS.REF IMMUNITY V. 36 646 2012REFN ISSN 1074-7613PMID 22483802DOI 10.1016/J.IMMUNI.2012.03.009 Variant Set Distributions Mapped Variants
General Structure Information 3e1r CEP55 midbody targeting of the escrt machinery by a non-canonical coiled-coil in cep55 2.0Å AUTH H.H.LEE,N.ELIA,R.GHIRLANDO,J.LIPPINCOTT-SCHWARTZ,AUTH 2 J.H.HURLEYTITL MIDBODY TARGETING OF THE ESCRT MACHINERY BY ATITL 2 NONCANONICAL COILED COIL IN CEP55.REF SCIENCE V. 322 576 2008REFN ISSN 0036-8075PMID 18948538DOI 10.1126/SCIENCE.1162042 Variant Set Distributions Mapped Variants
General Structure Information 1wfo SDK2 the eighth fn3 domain of human sidekick-2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL THE EIGHTH FN3 DOMAIN OF HUMAN SIDEKICK-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kdd CDCA8 solution structure of the conserved c-terminal dimerization domain of borealin -1.0Å AUTH E.BOURHIS,A.LINGEL,Q.PHUNG,W.J.FAIRBROTHER,AUTH 2 A.G.COCHRANTITL PHOSPHORYLATION OF A BOREALIN DIMERIZATION DOMAINTITL 2 IS REQUIRED FOR PROPER CHROMOSOME SEGREGATION.REF BIOCHEMISTRY V. 48 6783 2009REFN ISSN 0006-2960PMID 19530738DOI 10.1021/BI900530V Variant Set Distributions Mapped Variants