General Structure Information 2box EMR2 egf domains 1,2,5 of human emr2, a 7-tm immune system molecule, in complex with strontium. 2.5Å AUTH R.J.M.ABBOTT,I.SPENDLOVE,P.ROVERSI,H.FITZGIBBON,V.KNOTT,AUTH 2 P.TERIETE,J.M.MCDONNELL,P.A.HANDFORD,S.M.LEATITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A NOVEL TTITL 2 CELL RECEPTOR CO-REGULATORY PROTEIN COMPLEX, CD97-CD55.REF J.BIOL.CHEM. V. 282 22023 2007REFN ISSN 0021-9258PMID 17449467DOI 10.1074/JBC.M702588200 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3vro CBLC crystal structure of the tyrosine kinase binding domain of cbl-c in complex with phospho-src peptide 1.8Å AUTH K.TAKESHITA,T.TEZUKA,Y.ISOZAKI,E.YAMASHITA,M.SUZUKI,M.KIM,AUTH 2 Y.YAMANASHI,T.YAMAMOTO,A.NAKAGAWATITL STRUCTURAL FLEXIBILITY REGULATES PHOSPHOPEPTIDE-BINDINGTITL 2 ACTIVITY OF THE TYROSINE KINASE BINDING DOMAIN OF CBL-C.REF J.BIOCHEM. V. 152 487 2012REFN ISSN 0021-924XPMID 22888118DOI 10.1093/JB/MVS085 Variant Set Distributions Mapped Variants
General Structure Information 1s18 CANT1 structure and protein design of human apyrase 1.7Å AUTH J.DAI,J.LIU,Y.DENG,T.M.SMITH,M.LUTITL STRUCTURE AND PROTEIN DESIGN OF A HUMAN PLATELETTITL 2 FUNCTION INHIBITOR.REF CELL(CAMBRIDGE,MASS.) V. 116 649 2004REFN ISSN 0092-8674PMID 15006348DOI 10.1016/S0092-8674(04)00172-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ma2 RASGRP2 solution structure of rasgrp2 ef hands bound to calcium -1.0Å AUTH J.S.IWIG,Y.VERCOULEN,R.DAS,T.BARROS,A.LIMNANDER,Y.CHE,AUTH 2 J.G.PELTON,D.E.WEMMER,J.P.ROOSE,J.KURIYANTITL STRUCTURAL ANALYSIS OF AUTOINHIBITION IN THE RAS-SPECIFICTITL 2 EXCHANGE FACTOR RASGRP1.REF ELIFE V. 2 00813 2013REFN ESSN 2050-084XPMID 23908768DOI 10.7554/ELIFE.00813 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4hre S100A10 crystal structure of p11/annexin a2 heterotetramer in complex with smarca3 peptide 2.79Å AUTH Y.S.OH,P.GAO,K.W.LEE,I.CEGLIA,J.S.SEO,X.ZHANG,J.H.AHN,AUTH 2 B.T.CHAIT,D.J.PATEL,Y.KIM,P.GREENGARDTITL SMARCA3, A CHROMATIN-REMODELING FACTOR, IS REQUIRED FORTITL 2 P11-DEPENDENT ANTIDEPRESSANT ACTION.REF CELL(CAMBRIDGE,MASS.) V. 152 831 2013REFN ISSN 0092-8674PMID 23415230DOI 10.1016/J.CELL.2013.01.014 Variant Set Distributions Mapped Variants
General Structure Information 4hre S100A10 crystal structure of p11/annexin a2 heterotetramer in complex with smarca3 peptide 2.79Å AUTH Y.S.OH,P.GAO,K.W.LEE,I.CEGLIA,J.S.SEO,X.ZHANG,J.H.AHN,AUTH 2 B.T.CHAIT,D.J.PATEL,Y.KIM,P.GREENGARDTITL SMARCA3, A CHROMATIN-REMODELING FACTOR, IS REQUIRED FORTITL 2 P11-DEPENDENT ANTIDEPRESSANT ACTION.REF CELL(CAMBRIDGE,MASS.) V. 152 831 2013REFN ISSN 0092-8674PMID 23415230DOI 10.1016/J.CELL.2013.01.014 Variant Set Distributions Mapped Variants
General Structure Information 3eto NOTCH1 2 angstrom xray structure of the notch1 negative regulatory region (nrr) 2.0Å AUTH W.R.GORDON,M.ROY,D.VARDAR-ULU,M.GARFINKEL,M.R.MANSOUR,AUTH 2 J.C.ASTER,S.C.BLACKLOWTITL STRUCTURE OF THE NOTCH1-NEGATIVE REGULATORY REGION:TITL 2 IMPLICATIONS FOR NORMAL ACTIVATION AND PATHOGENIC SIGNALINGTITL 3 IN T-ALL.REF BLOOD V. 113 4381 2009REFN ISSN 0006-4971PMID 19075186DOI 10.1182/BLOOD-2008-08-174748 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3uom CASQ1 ca2+ complex of human skeletal calsequestrin 2.02Å AUTH E.J.SANCHEZ,K.M.LEWIS,B.R.DANNA,C.KANGTITL HIGH-CAPACITY CA2+ BINDING OF HUMAN SKELETAL CALSEQUESTRIN.REF J.BIOL.CHEM. V. 287 11592 2012REFN ISSN 0021-9258PMID 22337878DOI 10.1074/JBC.M111.335075 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1emo FBN1 nmr study of a pair of fibrillin ca2+ binding epidermal growth factor-like domains, 22 structures -1.0Å AUTH A.K.DOWNING,V.KNOTT,J.M.WERNER,C.M.CARDY,AUTH 2 I.D.CAMPBELL,P.A.HANDFORDTITL SOLUTION STRUCTURE OF A PAIR OF CALCIUM-BINDINGTITL 2 EPIDERMAL GROWTH FACTOR-LIKE DOMAINS: IMPLICATIONSTITL 3 FOR THE MARFAN SYNDROME AND OTHER GENETICTITL 4 DISORDERS.REF CELL(CAMBRIDGE,MASS.) V. 85 597 1996REFN ISSN 0092-8674PMID […]
General Structure Information 2luc S100A11 solution structure of human s100 calcium-binding protein a11 -1.0Å AUTH K.W.HUNG,Y.M.CHANG,C.YUTITL NMR STRUCTURE NOTE: THE STRUCTURE OF HUMAN CALCIUM-BOUNDTITL 2 S100A11.REF J.BIOMOL.NMR V. 54 211 2012REFN ISSN 0925-2738PMID 22903637DOI 10.1007/S10858-012-9661-2 Variant Set Distributions Mapped Variants