Assessment of Structural Intolerance and Durability
General Structure Information 2jng CUL7 solution structure of the cul7-cph domain from homo sapiens; northeast structural genomics consortium target ht1. -1.0Å AUTH L.KAUSTOV,J.LUKIN,A.LEMAK,S.DUAN,M.HO,R.DOHERTY,AUTH 2 L.Z.PENN,C.H.ARROWSMITHTITL THE CONSERVED CPH DOMAINS OF CUL7 AND PARC ARETITL 2 PROTEIN-PROTEIN INTERACTION MODULES THAT BIND THETITL 3 TETRAMERIZATION DOMAIN OF P53REF J.BIOL.CHEM. V. 282 11300 2007REFN ISSN 0021-9258PMID 17298945DOI 10.1074/JBC.M611297200 […]
General Structure Information 2l5u CHD4 structure of the first phd finger (phd1) from chd4 (mi2b) -1.0Å AUTH R.E.MANSFIELD,C.A.MUSSELMAN,A.H.KWAN,S.S.OLIVER,A.L.GARSKE,AUTH 2 F.DAVRAZOU,J.M.DENU,T.G.KUTATELADZE,J.P.MACKAYTITL PLANT HOMEODOMAIN (PHD) FINGERS OF CHD4 ARE HISTONETITL 2 H3-BINDING MODULES WITH PREFERENCE FOR UNMODIFIED H3K4 ANDTITL 3 METHYLATED H3K9REF J.BIOL.CHEM. V. 286 11779 2011REFN ISSN 0021-9258PMID 21278251DOI 10.1074/JBC.M110.208207 Variant Set Distributions Mapped Variants
General Structure Information 3bua TERF2 crystal structure of trf2 trfh domain and apollo peptide complex 2.5Å AUTH Y.CHEN,Y.YANG,M.VAN OVERBEEK,J.R.DONIGIAN,P.BACIU,AUTH 2 T.DE LANGE,M.LEITITL A SHARED DOCKING MOTIF IN TRF1 AND TRF2 USED FORTITL 2 DIFFERENTIAL RECRUITMENT OF TELOMERIC PROTEINS.REF SCIENCE V. 319 1092 2008REFN ISSN 0036-8075PMID 18202258DOI 10.1126/SCIENCE.1151804 Variant Set Distributions Mapped Variants
General Structure Information 2mbg RALBP1 rlip76 (gap-gbd) -1.0Å AUTH K.V.RAJASEKAR,L.J.CAMPBELL,D.NIETLISPACH,D.OWEN,H.R.MOTTTITL THE STRUCTURE OF THE RLIP76 RHOGAP-RAL BINDING DOMAIN DYAD:TITL 2 FIXED POSITION OF THE DOMAINS LEADS TO DUAL ENGAGEMENT OFTITL 3 SMALL G PROTEINS AT THE MEMBRANE.REF STRUCTURE V. 21 2131 2013REFN ISSN 0969-2126PMID 24207123DOI 10.1016/J.STR.2013.09.007 Variant Set Distributions Mapped Variants
General Structure Information 1uap PCOLCE nmr structure of the ntr domain from human pcolce1 -1.0Å AUTH E.LIEPINSH,L.BANYAI,G.PINTACUDA,M.TREXLER,L.PATTHY,AUTH 2 G.OTTINGTITL NMR STRUCTURE OF THE NETRIN-LIKE DOMAIN (NTR) OFTITL 2 HUMAN TYPE I PROCOLLAGEN C-PROTEINASE ENHANCERTITL 3 DEFINES STRUCTURAL CONSENSUS OF NTR DOMAINS ANDTITL 4 ASSESSES POTENTIAL PROTEINASE INHIBITORY ACTIVITYTITL 5 AND LIGAND BINDING.REF J.BIOL.CHEM. V. 278 […]
General Structure Information 1em2 STARD3 star-related lipid transport domain of mln64 2.2Å AUTH Y.TSUJISHITA,J.H.HURLEYTITL STRUCTURE AND LIPID TRANSPORT MECHANISM OF A STAR-RELATEDTITL 2 DOMAIN.REF NAT.STRUCT.BIOL. V. 7 408 2000REFN ISSN 1072-8368PMID 10802740DOI 10.1038/75192 Variant Set Distributions Mapped Variants
General Structure Information 2qy7 CLINT1 crystal structure of human epsinr enth domain 2.0Å AUTH S.E.MILLER,B.M.COLLINS,A.J.MCCOY,M.S.ROBINSON,AUTH 2 D.J.OWENTITL A SNARE-ADAPTOR INTERACTION IS A NEW MODE OF CARGOTITL 2 RECOGNITION IN CLATHRIN-COATED VESICLES.REF NATURE V. 450 570 2007REFN ISSN 0028-0836PMID 18033301DOI 10.1038/NATURE06353 Variant Set Distributions Mapped Variants
General Structure Information 4hxi CUL3 crystal structure of klhl3/cul3 complex 3.51Å AUTH A.X.JI,G.G.PRIVETITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF KLHL3/CUL3TITL 2 COMPLEX AND IMPLICATIONS OF FHHT MUTATIONS IN CUL3 BINDINGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2me6 GBX1 nmr structure of the homeodomain transcription factor gbx1 from homo sapiens in complex with the dna sequence cgactaattagtcg -1.0Å AUTH A.PROUDFOOT,K.WUTHRICH,P.SERRANO,M.GERALTTITL NMR STRUCTURE OF THE HOMEODOMAIN TRANSCRIPTION FACTOR GBX1TITL 2 FROM HOMO SAPIENS IN COMPLEX WITH THE DNA SEQUENCETITL 3 CGACTAATTAGTCGREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1wgr GRB7 solution structure of the ra domain of human grb7 protein -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RA DOMAIN OF HUMAN GRB7TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants