Assessment of Structural Intolerance and Durability
General Structure Information 2ywk RBM11 crystal structure of rrm-domain derived from human putative rna-binding protein 11 1.54Å AUTH M.KAWAZOE,C.TAKEMOTO,T.KAMINISHI,T.UCHIKUBO-KAMO,AUTH 2 A.NISHINO,S.MORITA,T.TERADA,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF RRM-DOMAIN DERIVED FROM HUMANTITL 2 PUTATIVE RNA-BINDING PROTEIN 11REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1e17 FOXO4 solution structure of the dna binding domain of the human forkhead transcription factor afx (foxo4) -1.0Å AUTH J.WEIGELT,I.CLIMENT,K.DAHLMAN-WRIGHT,M.WIKSTROMTITL 1H, 13C AND 15N RESONANCE ASSIGNMENTS OF THE DNATITL 2 BINDING DOMAIN OF THE HUMAN FORKHEAD TRANSCRIPTIONTITL 3 FACTOR AFXREF J.BIOMOL.NMR V. 17 181 2000REFN ISSN 0925-2738PMID 10921784DOI 10.1023/A:1008358816478 Variant Set Distributions […]
General Structure Information 4j6s YWHAG 14-3-3gamma complexed with the n-terminal sequence of tyrosine hydroxylase (residues 1-43) 3.08Å AUTH A.A.SKJEVIK,M.MILENI,A.BAUMANN,O.HALSKAU,K.TEIGEN,AUTH 2 R.C.STEVENS,A.MARTINEZTITL THE N-TERMINAL SEQUENCE OF TYROSINE HYDROXYLASE IS ATITL 2 CONFORMATIONALLY VERSATILE MOTIF THAT BINDS 14-3-3 PROTEINSTITL 3 AND MEMBRANES.REF J.MOL.BIOL. V. 426 150 2014REFN ISSN 0022-2836PMID 24055376DOI 10.1016/J.JMB.2013.09.012 Variant Set Distributions Mapped Variants
General Structure Information 1ggl RBP5 human cellular retinol binding protein iii 2.31Å AUTH C.FOLLI,V.CALDERONE,S.OTTONELLO,A.BOLCHI,G.ZANOTTI,AUTH 2 M.STOPPINI,R.BERNITITL IDENTIFICATION, RETINOID BINDING, AND X-RAYTITL 2 ANALYSIS OF A HUMAN RETINOL-BINDING PROTEIN.REF PROC.NATL.ACAD.SCI.USA V. 98 3710 2001REFN ISSN 0027-8424PMID 11274389DOI 10.1073/PNAS.061455898 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2ctl HDLBP solution structure of the 13th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 13TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2v55 RND3 mechanism of multi-site phosphorylation from a rock-i:rhoe complex structure 3.7Å AUTH D.KOMANDER,R.GARG,P.T.C.WAN,A.J.RIDLEY,D.BARFORDTITL MECHANISM OF MULTI-SITE PHOSPHORYLATION FROM ATITL 2 ROCK-I:RHOE COMPLEX STRUCTURE.REF EMBO J. V. 27 3175 2008REFN ISSN 0261-4189PMID 18946488DOI 10.1038/EMBOJ.2008.226 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1rly GTF2B rdc-derived models of the zinc ribbon domain of human general transcription tfiib (zinc bound structures) -1.0Å AUTH M.GHOSH,L.M.ELSBY,T.K.MAL,J.M.GOODING,S.G.ROBERTS,AUTH 2 M.IKURATITL PROBING ZN2+-BINDING EFFECTS ON THE ZINC-RIBBONTITL 2 DOMAIN OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB.REF BIOCHEM.J. V. 378 317 2004REFN ISSN 0264-6021PMID 14641108DOI 10.1042/BJ20031706 Variant Set Distributions Mapped Variants
General Structure Information 2wcb S100A12 s100a12 complex with zinc in the absence of calcium 1.73Å AUTH O.V.MOROZ,E.V.BLAGOVA,A.J.WILKINSON,K.S.WILSON,I.B.BRONSTEINTITL THE CRYSTAL STRUCTURES OF HUMAN S100A12 IN APO FORM AND INTITL 2 COMPLEX WITH ZINC: NEW INSIGHTS INTO S100A12TITL 3 OLIGOMERISATION.REF J.MOL.BIOL. V. 391 536 2009REFN ISSN 0022-2836PMID 19501594DOI 10.1016/J.JMB.2009.06.004 Variant Set Distributions Mapped Variants
General Structure Information 1mhd SMAD3 crystal structure of a smad mh1 domain bound to dna 2.8Å AUTH Y.SHI,Y.F.WANG,L.JAYARAMAN,H.YANG,J.MASSAGUE,AUTH 2 N.P.PAVLETICHTITL CRYSTAL STRUCTURE OF A SMAD MH1 DOMAIN BOUND TOTITL 2 DNA: INSIGHTS ON DNA BINDING IN TGF-BETA SIGNALING.REF CELL(CAMBRIDGE,MASS.) V. 94 585 1998REFN ISSN 0092-8674PMID 9741623DOI 10.1016/S0092-8674(00)81600-1 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1×50 LGALS4 solution structure of the c-terminal gal-bind lectin domain from human galectin-4 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL GAL-BINDTITL 2 LECTIN DOMAIN FROM HUMAN GALECTIN-4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants