General Structure Information
| PDB ID | 2v55 |
| HGNC Gene Label(s) | RND3 |
| Structure Name | mechanism of multi-site phosphorylation from a rock-i:rhoe complex structure |
| Resolution | 3.7Å |
| Reference | AUTH D.KOMANDER,R.GARG,P.T.C.WAN,A.J.RIDLEY,D.BARFORDTITL MECHANISM OF MULTI-SITE PHOSPHORYLATION FROM ATITL 2 ROCK-I:RHOE COMPLEX STRUCTURE.REF EMBO J. V. 27 3175 2008REFN ISSN 0261-4189PMID 18946488DOI 10.1038/EMBOJ.2008.226 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 182 |
| Number Of SNVs | 41 |
| Number Of Permutations | 19914 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.3 |
| p-value | 0.007 |
COSMIC
| Number Of Residues | 182 |
| Number Of SNVs | 4 |
| Number Of Permutations | 793 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.167 |
| p-value | 0.754 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.265 |
| p-value | 1.0 |