Assessment of Structural Intolerance and Durability
General Structure Information 3f62 IL18 crystal structure of human il-18 in complex with ectromelia virus il- 18 binding protein 2.0Å AUTH B.KRUMM,X.MENG,Y.LI,Y.XIANG,J.DENGTITL STRUCTURAL BASIS FOR ANTAGONISM OF HUMAN INTERLEUKIN 18 BYTITL 2 POXVIRUS INTERLEUKIN 18-BINDING PROTEIN.REF PROC.NATL.ACAD.SCI.USA V. 105 20711 2008REFN ISSN 0027-8424PMID 19104048DOI 10.1073/PNAS.0809086106 Variant Set Distributions Mapped Variants
General Structure Information 3f62 IL18 crystal structure of human il-18 in complex with ectromelia virus il- 18 binding protein 2.0Å AUTH B.KRUMM,X.MENG,Y.LI,Y.XIANG,J.DENGTITL STRUCTURAL BASIS FOR ANTAGONISM OF HUMAN INTERLEUKIN 18 BYTITL 2 POXVIRUS INTERLEUKIN 18-BINDING PROTEIN.REF PROC.NATL.ACAD.SCI.USA V. 105 20711 2008REFN ISSN 0027-8424PMID 19104048DOI 10.1073/PNAS.0809086106 Variant Set Distributions Mapped Variants
General Structure Information 3f62 IL18 crystal structure of human il-18 in complex with ectromelia virus il- 18 binding protein 2.0Å AUTH B.KRUMM,X.MENG,Y.LI,Y.XIANG,J.DENGTITL STRUCTURAL BASIS FOR ANTAGONISM OF HUMAN INTERLEUKIN 18 BYTITL 2 POXVIRUS INTERLEUKIN 18-BINDING PROTEIN.REF PROC.NATL.ACAD.SCI.USA V. 105 20711 2008REFN ISSN 0027-8424PMID 19104048DOI 10.1073/PNAS.0809086106 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 2hye CUL4A crystal structure of the ddb1-cul4a-rbx1-sv5v complex 3.1Å AUTH S.ANGERS,T.LI,X.YI,M.J.MACCOSS,R.T.MOON,N.ZHENGTITL MOLECULAR ARCHITECTURE AND ASSEMBLY OF THETITL 2 DDB1-CUL4A UBIQUITIN LIGASE MACHINERY.REF NATURE V. 443 590 2006REFN ISSN 0028-0836PMID 16964240DOI 10.1038/NATURE05175 Variant Set Distributions Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Mapped Variants
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2aze E2F1 structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer 2.55Å AUTH S.M.RUBIN,A.L.GALL,N.ZHENG,N.P.PAVLETICHTITL STRUCTURE OF THE RB C-TERMINAL DOMAIN BOUND TOTITL 2 E2F1-DP1: A MECHANISM FOR PHOSPHORYLATION-INDUCEDTITL 3 E2F RELEASE.REF CELL(CAMBRIDGE,MASS.) V. 123 1093 2005REFN ISSN 0092-8674PMID 16360038DOI 10.1016/J.CELL.2005.09.044 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3f8u TAPBP tapasin/erp57 heterodimer 2.6Å AUTH G.DONG,P.A.WEARSCH,D.R.PEAPER,P.CRESSWELL,K.M.REINISCHTITL INSIGHTS INTO MHC CLASS I PEPTIDE LOADING FROM THE STRUCTURETITL 2 OF THE TAPASIN-ERP57 THIOL OXIDOREDUCTASE HETERODIMER.REF IMMUNITY V. 30 21 2009REFN ISSN 1074-7613PMID 19119025DOI 10.1016/J.IMMUNI.2008.10.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants