Assessment of Structural Intolerance and Durability
General Structure Information 1xwn PPIL1 solution structure of cyclophilin like 1(ppil1) and insights into its interaction with skip -1.0Å AUTH C.XU,J.ZHANG,X.HUANG,J.SUN,Y.XU,Y.TANG,J.WU,Y.SHI,AUTH 2 Q.HUANG,Q.ZHANGTITL SOLUTION STRUCTURE OF HUMAN PEPTIDYL PROLYLTITL 2 ISOMERASE LIKE PROTEIN 1 AND INSIGHTS INTO ITSTITL 3 INTERACTION WITH SKIPREF J.BIOL.CHEM. V. 281 15900 2006REFN ISSN 0021-9258PMID 16595688DOI 10.1074/JBC.M511155200 Variant Set Distributions Mapped […]
General Structure Information 3qfv CDC42BPB mrck beta in complex with tpca-1 2.65Å AUTH T.HEIKKILA,E.WHEATLEY,D.CRIGHTON,E.SCHRODER,A.BOAKES,AUTH 2 S.J.KAYE,M.MEZNA,L.PANG,M.RUSHBROOKE,A.TURNBULL,M.F.OLSONTITL CO-CRYSTAL STRUCTURES OF INHIBITORS WITH MRCK BETA , A KEYTITL 2 REGULATOR OF TUMOR CELL INVASION.REF PLOS ONE V. 6 24825 2011REFN ESSN 1932-6203PMID 21949762DOI 10.1371/JOURNAL.PONE.0024825 Variant Set Distributions Mapped Variants
General Structure Information 3cw3 AIM1 crystal structure of aim1g1 1.88Å AUTH P.ARAVIND,G.WISTOW,Y.SHARMA,R.SANKARANARAYANANTITL EXPLORING THE LIMITS OF SEQUENCE AND STRUCTURE IN A VARIANTTITL 2 BETAGAMMA-CRYSTALLIN DOMAIN OF THE PROTEIN ABSENT INTITL 3 MELANOMA-1 (AIM1).REF J.MOL.BIOL. V. 381 509 2008REFN ISSN 0022-2836PMID 18582473DOI 10.1016/J.JMB.2008.06.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2ns2 SPIN1 crystal structure of spindlin1 2.2Å AUTH Q.ZHAO,L.QIN,F.JIANG,B.WU,W.YUE,F.XU,Z.RONG,H.YUAN,AUTH 2 X.XIE,Y.GAO,C.BAI,M.BARTLAM,X.PEI,Z.RAOTITL STRUCTURE OF HUMAN SPINDLIN1. TANDEM TUDOR-LIKETITL 2 DOMAINS FOR CELL CYCLE REGULATIONREF J.BIOL.CHEM. V. 282 647 2007REFN ISSN 0021-9258PMID 17082182DOI 10.1074/JBC.M604029200 Variant Set Distributions Mapped Variants
General Structure Information 1r4x COPG1 crystal structure analys of the gamma-copi appendage domain 1.9Å AUTH P.J.WATSON,G.FRIGERIO,B.M.COLLINS,R.DUDEN,D.J.OWENTITL GAMMA-COP APPENDAGE DOMAIN – STRUCTURE AND FUNCTIONREF TRAFFIC V. 5 79 2004REFN ISSN 1398-9219PMID 14690497DOI 10.1111/J.1600-0854.2004.00158.X Variant Set Distributions Mapped Variants
General Structure Information 4akm LAMP3 crystal structure of the human lysosome-associated membrane protein lamp-3 (aka dc-lamp) 2.69Å AUTH S.WILKE,J.KRAUSZE,K.BUSSOWTITL CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN OF THE DCTITL 2 LYSOSOMAL ASSOCIATED MEMBRANE PROTEIN: IMPLICATIONS FOR THETITL 3 LYSOSOMAL GLYCOCALYX.REF BMC BIOL. V. 10 62 2012REFN ISSN 1741-7007PMID 22809326DOI 10.1186/1741-7007-10-62 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1rl1 SUGT1 solution structure of human sgt1 cs domain -1.0Å AUTH Y.-T.LEE,J.JACOB,W.MICHOWSKI,M.NOWOTNY,J.KUZNICKI,AUTH 2 W.J.CHAZINTITL HUMAN SGT1 BINDS HSP90 THROUGH THE CHORD-SGT1TITL 2 DOMAIN AND NOT THE TETRATRICOPEPTIDE REPEAT DOMAINREF J.BIOL.CHEM. V. 279 16511 2004REFN ISSN 0021-9258PMID 14761955DOI 10.1074/JBC.M400215200 Variant Set Distributions Mapped Variants
General Structure Information 2pso STARD13 human stard13 (dlc2) lipid transfer and protein localization domain 2.8Å AUTH A.G.THORSELL,W.H.LEE,C.PERSSON,M.I.SIPONEN,M.NILSSON,AUTH 2 R.D.BUSAM,T.KOTENYOVA,H.SCHULER,L.LEHTIOTITL COMPARATIVE STRUCTURAL ANALYSIS OF LIPID BINDING STARTTITL 2 DOMAINS.REF PLOS ONE V. 6 19521 2011REFN ESSN 1932-6203PMID 21738568DOI 10.1371/JOURNAL.PONE.0019521 Variant Set Distributions Mapped Variants
General Structure Information 1uff ITSN2 solution structure of the first sh3 domain of human intersectin2 (kiaa1256) -1.0Å AUTH N.KOBAYASHI,T.KIGAWA,S.KOSHIBA,N.TOCHIO,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST SH3 DOMAIN OFTITL 2 HUMAN INTERSECTIN2 (KIAA1256)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1wj3 CNTN3 solution structure of the fourth fn3 domain of kiaa1496 protein -1.0Å AUTH K.INOUE,T.NAGASHIMA,N.TOCHIO,T.KIGAWA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH FN3 DOMAIN OFTITL 2 KIAA1496 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants