Assessment of Structural Intolerance and Durability
General Structure Information 4imn PTGDS crystal structure of wild type human lipocalin pgds bound with peg mme 2000 2.09Å AUTH S.M.LIM,D.CHEN,H.TEO,A.ROOS,A.E.JANSSON,T.NYMAN,AUTH 2 L.TRESAUGUES,K.PERVUSHIN,P.NORDLUNDTITL STRUCTURAL AND DYNAMIC INSIGHTS INTO SUBSTRATE BINDING ANDTITL 2 CATALYSIS OF HUMAN LIPOCALIN PROSTAGLANDIN D SYNTHASE.REF J.LIPID RES. V. 54 1630 2013REFN ISSN 0022-2275PMID 23526831DOI 10.1194/JLR.M035410 Variant Set Distributions Mapped Variants
General Structure Information 4mxw LTBR structure of heterotrimeric lymphotoxin lta1b2 bound to lymphotoxin beta receptor ltbr and anti-lta fab 3.6Å AUTH J.SUDHAMSU,J.YIN,E.Y.CHIANG,M.A.STAROVASNIK,J.L.GROGAN,AUTH 2 S.G.HYMOWITZTITL DIMERIZATION OF LT BETA R BY LT ALPHA 1 BETA 2 IS NECESSARYTITL 2 AND SUFFICIENT FOR SIGNAL TRANSDUCTION.REF PROC.NATL.ACAD.SCI.USA V. 110 19896 2013REFN ISSN 0027-8424PMID 24248355DOI 10.1073/PNAS.1310838110 Variant Set Distributions […]
General Structure Information 2fs7 CRABP2 crystal structure of apo-cellular retinoic acid binding protein type ii at 1.55 angstroms resolution 1.55Å AUTH S.VAEZESLAMI,E.MATHES,C.VASILEIOU,B.BORHAN,AUTH 2 J.H.GEIGERTITL THE STRUCTURE OF APO-WILD-TYPE CELLULAR RETINOICTITL 2 ACID BINDING PROTEIN II AT 1.4 A AND ITSTITL 3 RELATIONSHIP TO LIGAND BINDING AND NUCLEARTITL 4 TRANSLOCATION.REF J.MOL.BIOL. V. 363 687 2006REFN ISSN […]
General Structure Information 1n3h SHC1 coupling of folding and binding in the ptb domain of the signaling protein shc -1.0Å AUTH A.FAROOQ,L.ZENG,K.S.YAN,K.S.RAVICHANDRAN,M.-M.ZHOUTITL COUPLING OF FOLDING AND BINDING IN THE PTB DOMAINTITL 2 OF THE SIGNALING PROTEIN SHCREF STRUCTURE V. 11 905 2003REFN ISSN 0969-2126PMID 12906822DOI 10.1016/S0969-2126(03)00134-5 Variant Set Distributions Mapped Variants
General Structure Information 1he3 BLVRB human biliverdin ix beta reductase: nadp/mesobiliverdin iv alpha ternary complex 1.4Å AUTH P.J.B.PEREIRA,S.MACEDO-RIBEIRO,A.PARRAGA,AUTH 2 R.PEREZ-LUQUE,O.CUNNINGHAM,K.DARCY,T.J.MANTLE,AUTH 3 M.COLLTITL STRUCTURE OF HUMAN BILIVERDIN IX BETA REDUCTASE,TITL 2 AN EARLY FETAL BILIRUBIN IX PRODUCING ENZYMEREF NAT.STRUCT.BIOL. V. 8 215 2001REFN ISSN 1072-8368PMID 11224564DOI 10.1038/84948 Variant Set Distributions Mapped Variants
General Structure Information 2rbl TNC high resolution design of a protein loop 2.1Å AUTH X.HU,H.WANG,H.KE,B.KUHLMANTITL HIGH-RESOLUTION DESIGN OF A PROTEIN LOOP.REF PROC.NATL.ACAD.SCI.USA V. 104 17668 2007REFN ISSN 0027-8424PMID 17971437DOI 10.1073/PNAS.0707977104 Variant Set Distributions Mapped Variants