Assessment of Structural Intolerance and Durability
General Structure Information 1em2 STARD3 star-related lipid transport domain of mln64 2.2Å AUTH Y.TSUJISHITA,J.H.HURLEYTITL STRUCTURE AND LIPID TRANSPORT MECHANISM OF A STAR-RELATEDTITL 2 DOMAIN.REF NAT.STRUCT.BIOL. V. 7 408 2000REFN ISSN 1072-8368PMID 10802740DOI 10.1038/75192 Variant Set Distributions Mapped Variants
General Structure Information 3bhh CAMK2B crystal structure of human calcium/calmodulin-dependent protein kinase iib isoform 1 (camk2b) 2.4Å AUTH P.FILIPPAKOPOULOS,P.RELLOS,F.NIESEN,N.BURGESS,A.BULLOCK,AUTH 2 G.BERRIDGE,A.C.W.PIKE,E.UGOCHUKWU,E.S.PILKA,F.VON DELFT,AUTH 3 C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN CALCIUM/CALMODULIN-DEPENDENTTITL 2 PROTEIN KINASE IIB ISOFORM 1 (CAMK2B).REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2aze TFDP1 structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer 2.55Å AUTH S.M.RUBIN,A.L.GALL,N.ZHENG,N.P.PAVLETICHTITL STRUCTURE OF THE RB C-TERMINAL DOMAIN BOUND TOTITL 2 E2F1-DP1: A MECHANISM FOR PHOSPHORYLATION-INDUCEDTITL 3 E2F RELEASE.REF CELL(CAMBRIDGE,MASS.) V. 123 1093 2005REFN ISSN 0092-8674PMID 16360038DOI 10.1016/J.CELL.2005.09.044 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3aih OS9 human os-9 mrh domain complexed with alpha3,alpha6-man5 2.1Å AUTH T.SATOH,Y.CHEN,D.HU,S.HANASHIMA,K.YAMAMOTO,Y.YAMAGUCHITITL STRUCTURAL BASIS FOR OLIGOSACCHARIDE RECOGNITION OFTITL 2 MISFOLDED GLYCOPROTEINS BY OS-9 IN ER-ASSOCIATED DEGRADATIONREF MOL.CELL V. 40 905 2010REFN ISSN 1097-2765PMID 21172656DOI 10.1016/J.MOLCEL.2010.11.017 Variant Set Distributions Mapped Variants
General Structure Information 1fyv TLR1 crystal structure of the tir domain of human tlr1 2.9Å AUTH Y.XU,X.TAO,B.SHEN,T.HORNG,R.MEDZHITOV,J.L.MANLEY,AUTH 2 L.TONGTITL STRUCTURAL BASIS FOR SIGNAL TRANSDUCTION BY THETITL 2 TOLL/INTERLEUKIN-1 RECEPTOR DOMAINS.REF NATURE V. 408 111 2000REFN ISSN 0028-0836PMID 11081518DOI 10.1038/35047056 Variant Set Distributions Mapped Variants
General Structure Information 1fyv TLR1 crystal structure of the tir domain of human tlr1 2.9Å AUTH Y.XU,X.TAO,B.SHEN,T.HORNG,R.MEDZHITOV,J.L.MANLEY,AUTH 2 L.TONGTITL STRUCTURAL BASIS FOR SIGNAL TRANSDUCTION BY THETITL 2 TOLL/INTERLEUKIN-1 RECEPTOR DOMAINS.REF NATURE V. 408 111 2000REFN ISSN 0028-0836PMID 11081518DOI 10.1038/35047056 Variant Set Distributions Mapped Variants
General Structure Information 1fyv TLR1 crystal structure of the tir domain of human tlr1 2.9Å AUTH Y.XU,X.TAO,B.SHEN,T.HORNG,R.MEDZHITOV,J.L.MANLEY,AUTH 2 L.TONGTITL STRUCTURAL BASIS FOR SIGNAL TRANSDUCTION BY THETITL 2 TOLL/INTERLEUKIN-1 RECEPTOR DOMAINS.REF NATURE V. 408 111 2000REFN ISSN 0028-0836PMID 11081518DOI 10.1038/35047056 Variant Set Distributions Mapped Variants
General Structure Information 1x3b TGFBI solution structure of the fas1 domain of human transforming growth factor-beta induced protein ig-h3 -1.0Å AUTH M.YONEYAMA,T.TOMIZAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FAS1 DOMAIN OF HUMANTITL 2 TRANSFORMING GROWTH FACTOR-BETA INDUCED PROTEINTITL 3 IG-H3REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1x3b TGFBI solution structure of the fas1 domain of human transforming growth factor-beta induced protein ig-h3 -1.0Å AUTH M.YONEYAMA,T.TOMIZAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FAS1 DOMAIN OF HUMANTITL 2 TRANSFORMING GROWTH FACTOR-BETA INDUCED PROTEINTITL 3 IG-H3REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1x3b TGFBI solution structure of the fas1 domain of human transforming growth factor-beta induced protein ig-h3 -1.0Å AUTH M.YONEYAMA,T.TOMIZAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FAS1 DOMAIN OF HUMANTITL 2 TRANSFORMING GROWTH FACTOR-BETA INDUCED PROTEINTITL 3 IG-H3REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants