Assessment of Structural Intolerance and Durability
General Structure Information 3evi PDCL2 crystal structure of the thioredoxin-fold domain of human phosducin- like protein 2 2.7Å AUTH X.LOU,R.BAO,C.Z.ZHOU,Y.CHENTITL STRUCTURE OF THE THIOREDOXIN-FOLD DOMAIN OF HUMANTITL 2 PHOSDUCIN-LIKE PROTEIN 2REF ACTA CRYSTALLOGR.,SECT.F V. 65 67 2009REFN ESSN 1744-3091PMID 19193988DOI 10.1107/S1744309108037342 Variant Set Distributions Mapped Variants
General Structure Information 3kt9 APTX aprataxin fha domain 1.65Å AUTH O.J.BECHEREL,B.JAKOB,A.L.CHERRY,N.GUEVEN,M.FUSSER,AUTH 2 A.W.KIJAS,C.PENG,S.KATYAL,P.J.MCKINNON,J.CHEN,AUTH 3 B.EPE,S.J.SMERDON,G.TAUCHER-SCHOLZ,M.F.LAVINTITL CK2 PHOSPHORYLATION-DEPENDENT INTERACTION BETWEENTITL 2 APRATAXIN AND MDC1 IN THE DNA DAMAGE RESPONSE.REF NUCLEIC ACIDS RES. V. 38 1489 2010REFN ISSN 0305-1048PMID 20008512DOI 10.1093/NAR/GKP1149 Variant Set Distributions Mapped Variants
General Structure Information 3uyj KDM8 crystal structure of jmjd5 catalytic core domain in complex with nickle and alpha-kg 2.35Å AUTH X.SU,H.LITITL CRYSTAL STRUCTURE OF JMJD5 CATALYTIC CORE DOMAIN IN COMPLEXTITL 2 WITH NICKLE AND ALPHA-KGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3g1n HUWE1 catalytic domain of the human e3 ubiquitin-protein ligase huwe1 2.6Å AUTH J.R.WALKER,L.QIU,Y.LI,T.DAVIS,W.TEMPEL,J.WEIGELT,AUTH 2 C.BOUNTRA,C.H.ARROWSMITH,A.M.EDWARDS,A.BOTCHKAREV,AUTH 3 S.DHE-PAGANONTITL HECT DOMAIN OF HUMAN HUWE1/MULEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3um1 BROX crystal structure of the brox bro1 domain in complex with the c- terminal tail of chmp5 2.71Å AUTH R.MU,V.DUSSUPT,J.JIANG,P.SETTE,V.RUDD,W.CHUENCHOR,N.F.BELLO,AUTH 2 F.BOUAMR,T.S.XIAOTITL TWO DISTINCT BINDING MODES DEFINE THE INTERACTION OF BROXTITL 2 WITH THE C-TERMINAL TAILS OF CHMP5 AND CHMP4B.REF STRUCTURE V. 20 887 2012REFN ISSN 0969-2126PMID 22484091DOI 10.1016/J.STR.2012.03.001 Variant Set […]
General Structure Information 2z4f DDR2 solution structure of the discoidin domain of ddr2 -1.0Å AUTH O.ICHIKAWA,M.OSAWA,N.NISHIDA,N.GOSHIMA,N.NOMURA,AUTH 2 I.SHIMADATITL STRUCTURAL BASIS OF THE COLLAGEN-BINDING MODE OFTITL 2 DISCOIDIN DOMAIN RECEPTOR 2REF EMBO J. V. 26 4168 2007REFN ISSN 0261-4189PMID 17703188DOI 10.1038/SJ.EMBOJ.7601833 Variant Set Distributions Mapped Variants
General Structure Information 2yrb RPGRIP1L solution structure of the first c2 domain from human kiaa1005 protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN FROMTITL 2 HUMAN KIAA1005 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ep6 MCTP2 solution structure of the second c2 domain from human mctp2 protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND C2 DOMAIN FROMTITL 2 HUMAN MCTP2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4doh IL20RB il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Mapped Variants
General Structure Information 1uhc DNMBP solution structure of rsgi ruh-002, a sh3 domain of kiaa1010 protein [homo sapiens] -1.0Å AUTH T.ABE,H.HIROTA,N.KOBAYASHI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-002, A SH3 DOMAINTITL 2 OF KIAA1010 PROTEIN [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants