Assessment of Structural Intolerance and Durability
General Structure Information 1du3 TNFRSF10B crystal structure of trail-sdr5 2.2Å AUTH S.-S.CHA,B.-J.SUNG,Y.A.KIM,Y.L.SONG,H.J.KIM,S.KIM,AUTH 2 M.S.LEE,B.-H.OHTITL CRYSTAL STRUCTURE OF TRAIL-DR5 COMPLEX IDENTIFIESTITL 2 A CRITICAL ROLE OF THE UNIQUE FRAME INSERTION INTITL 3 CONFERRING RECOGNITION SPECIFICITYREF J.BIOL.CHEM. V. 275 31171 2000REFN ISSN 0021-9258PMID 10893238DOI 10.1074/JBC.M004414200 Variant Set Distributions Mapped Variants
General Structure Information 3ygs APAF1 apaf-1 card in complex with prodomain of procaspase-9 2.5Å AUTH H.QIN,S.M.SRINIVASULA,G.WU,T.FERNANDES-ALNEMRI,AUTH 2 E.S.ALNEMRI,Y.SHITITL STRUCTURAL BASIS OF PROCASPASE-9 RECRUITMENT BYTITL 2 THE APOPTOTIC PROTEASE-ACTIVATING FACTOR 1.REF NATURE V. 399 549 1999REFN ISSN 0028-0836PMID 10376594DOI 10.1038/21124 Variant Set Distributions Mapped Variants
General Structure Information 3h11 CFLAR zymogen caspase-8:c-flipl protease domain complex 1.9Å AUTH J.W.YU,P.D.JEFFREY,Y.SHITITL MECHANISM OF PROCASPASE-8 ACTIVATION BY C-FLIPL.REF PROC.NATL.ACAD.SCI.USA V. 106 8169 2009REFN ISSN 0027-8424PMID 19416807DOI 10.1073/PNAS.0812453106 Variant Set Distributions Mapped Variants
General Structure Information 2r5t SGK1 crystal structure of inactive serum and glucocorticoid- regulated kinase 1 in complex with amp-pnp 1.9Å AUTH B.ZHAO,R.LEHR,A.M.SMALLWOOD,T.F.HO,K.MALEY,AUTH 2 T.RANDALL,M.S.HEAD,K.K.KORETKE,C.G.SCHNACKENBERGTITL CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF SERUMTITL 2 AND GLUCOCORTICOID-REGULATED KINASE 1 IN COMPLEXTITL 3 WITH AMP PNP.REF PROTEIN SCI. V. 16 2761 2007REFN ISSN 0961-8368PMID 17965184DOI 10.1110/PS.073161707 Variant Set […]
General Structure Information 3fdl BCL2L11 bim bh3 peptide in complex with bcl-xl 1.78Å AUTH E.F.LEE,J.D.SADOWSKY,B.J.SMITH,P.E.CZABOTAR,AUTH 2 K.J.PETERSON-KAUFMAN,P.M.COLMAN,S.H.GELLMAN,AUTH 3 W.D.FAIRLIETITL HIGH-RESOLUTION STRUCTURAL CHARACTERIZATION OF ATITL 2 HELICAL ALPHA/BETA-PEPTIDE FOLDAMER BOUND TO THETITL 3 ANTI-APOPTOTIC PROTEIN BCL-X(L)REF ANGEW.CHEM.INT.ED.ENGL. V. 48 4318 2009REFN ISSN 1433-7851PMID 19229915DOI 10.1002/ANIE.200805761 Variant Set Distributions Mapped Variants
General Structure Information 2qa7 HIP1 crystal structure of huntingtin-interacting protein 1 (hip1) coiled-coil domain with a basic surface suitable for hip-protein interactor (hippi) 2.8Å AUTH J.A.YBE,Q.NIUTITL CRYSTAL STRUCTURE AT 2.8 A OFTITL 2 HUNTINGTIN-INTERACTING PROTEIN 1 (HIP1)TITL 3 COILED-COIL DOMAIN REVEALS A CHARGED SURFACETITL 4 SUITABLE FOR HIP1 PROTEIN INTERACTOR (HIPPI)REF J.MOL.BIOL. V. 375 1197 […]