General Structure Information
| PDB ID | 2r5t |
| HGNC Gene Label(s) | SGK1 |
| Structure Name | crystal structure of inactive serum and glucocorticoid- regulated kinase 1 in complex with amp-pnp |
| Resolution | 1.9Å |
| Reference | AUTH B.ZHAO,R.LEHR,A.M.SMALLWOOD,T.F.HO,K.MALEY,AUTH 2 T.RANDALL,M.S.HEAD,K.K.KORETKE,C.G.SCHNACKENBERGTITL CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF SERUMTITL 2 AND GLUCOCORTICOID-REGULATED KINASE 1 IN COMPLEXTITL 3 WITH AMP PNP.REF PROTEIN SCI. V. 16 2761 2007REFN ISSN 0961-8368PMID 17965184DOI 10.1110/PS.073161707 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 284 |
| Number Of SNVs | 46 |
| Number Of Permutations | 5744 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.186 |
| p-value | 0.221 |
COSMIC
| Number Of Residues | 284 |
| Number Of SNVs | 3 |
| Number Of Permutations | 107 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.237 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
