Assessment of Structural Intolerance and Durability
General Structure Information 2k4t VDAC1 solution structure of human vdac-1 in ldao micelles -1.0Å AUTH S.HILLER,R.G.GARCES,T.J.MALIA,V.Y.OREKHOV,AUTH 2 M.COLOMBINI,G.WAGNERTITL SOLUTION STRUCTURE OF THE INTEGRAL HUMAN MEMBRANETITL 2 PROTEIN VDAC-1 IN DETERGENT MICELLES.REF SCIENCE V. 321 1206 2008REFN ISSN 0036-8075PMID 18755977DOI 10.1126/SCIENCE.1161302 Variant Set Distributions Mapped Variants
General Structure Information 3ky9 VAV1 autoinhibited vav1 2.73Å AUTH B.YU,I.R.MARTINS,P.LI,G.K.AMARASINGHE,J.UMETANI,AUTH 2 M.E.FERNANDEZ-ZAPICO,D.D.BILLADEAU,M.MACHIUS,D.R.TOMCHICK,AUTH 3 M.K.ROSENTITL STRUCTURAL AND ENERGETIC MECHANISMS OF COOPERATIVETITL 2 AUTOINHIBITION AND ACTIVATION OF VAV1REF CELL(CAMBRIDGE,MASS.) V. 140 246 2010REFN ISSN 0092-8674PMID 20141838DOI 10.1016/J.CELL.2009.12.033 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1op8 GZMA crystal structure of human granzyme a 2.5Å AUTH C.HINK-SCHAUER,E.ESTEBANEZ-PERPINA,F.KURSCHUS,AUTH 2 W.BODE,D.JENNETITL CRYSTAL STRUCTURE OF THE APOPTOSIS-INDUCING HUMANTITL 2 GRANZYME A DIMERREF NAT.STRUCT.BIOL. V. 10 535 2003REFN ISSN 1072-8368PMID 12819770DOI 10.1038/NSB945 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dbf NFKB1 solution structure of the death domain in human nuclear factor nf-kappa-b p105 subunit -1.0Å AUTH K.SAITO,M.INOUE,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEATH DOMAIN IN HUMANTITL 2 NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNITREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l86 IAPP solution nmr structure of human amylin in sds micelles at ph 7.3 -1.0Å AUTH R.P.NANGA,J.R.BRENDER,S.VIVEKANANDAN,A.RAMAMOORTHYTITL STRUCTURE AND MEMBRANE ORIENTATION OF IAPP IN ITS NATIVELYTITL 2 AMIDATED FORM AT PHYSIOLOGICAL PH IN A MEMBRANE ENVIRONMENT.REF BIOCHIM.BIOPHYS.ACTA V.1808 2337 2011REFN ISSN 0006-3002PMID 21723249DOI 10.1016/J.BBAMEM.2011.06.012 Variant Set Distributions Mapped Variants
General Structure Information 2mb9 BCL10 human bcl10 card -1.0Å AUTH Q.QIAO,C.YANG,C.ZHENG,L.FONTAN,L.DAVID,X.YU,C.BRACKEN,AUTH 2 M.ROSEN,A.MELNICK,E.H.EGELMAN,H.WUTITL STRUCTURAL ARCHITECTURE OF THE CARMA1/BCL10/MALT1TITL 2 SIGNALOSOME: NUCLEATION-INDUCED FILAMENTOUS ASSEMBLY.REF MOL.CELL V. 51 766 2013REFN ISSN 1097-2765PMID 24074955DOI 10.1016/J.MOLCEL.2013.08.032 Variant Set Distributions Mapped Variants
General Structure Information 1m6i AIFM1 crystal structure of apoptosis inducing factor (aif) 1.8Å AUTH H.YE,C.CANDE,N.C.STEPHANOU,S.JIANG,S.GURBUXANI,AUTH 2 N.LAROCHETTE,E.DAUGAS,C.GARRIDO,G.KROEMER,H.WUTITL DNA BINDING IS REQUIRED FOR THE APOPTOGENIC ACTIONTITL 2 OF APOPTOSIS INDUCING FACTOR.REF NAT.STRUCT.BIOL. V. 9 680 2002REFN ISSN 1072-8368PMID 12198487DOI 10.1038/NSB836 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3u3v TNFRSF21 the s-sad phased crystal structure of the ecto-domain of death receptor 6 (dr6) 2.96Å AUTH H.RU,L.X.ZHAO,W.DING,L.Y.JIAO,N.SHAW,W.LIANG,L.G.ZHANG,AUTH 2 L.W.HUNG,N.MATSUGAKI,S.WAKATSUKI,Z.J.LIUTITL S-SAD PHASING STUDY OF DEATH RECEPTOR 6 AND ITS SOLUTIONTITL 2 CONFORMATION REVEALED BY SAXSREF ACTA CRYSTALLOGR.,SECT.D V. 68 521 2012REFN ISSN 0907-4449PMID 22525750DOI 10.1107/S0907444912004490 Variant Set Distributions Mapped Variants
General Structure Information 3lm0 STK17B crystal structure of human serine/threonine kinase 17b (stk17b) 2.35Å Variant Set Distributions Mapped Variants
General Structure Information 2zne PDCD6 crystal structure of zn2+-bound form of des3-23alg-2 complexed with alix abs peptide 2.2Å AUTH H.SUZUKI,M.KAWASAKI,T.INUZUKA,M.OKUMURA,T.KAKIUCHI,AUTH 2 H.SHIBATA,S.WAKATSUKI,M.MAKITITL STRUCTURAL BASIS FOR CA(2+)-DEPENDENT FORMATION OFTITL 2 ALG-2/ALIX PEPTIDE COMPLEX: CA(2+)/EF3-DRIVENTITL 3 ARGININE SWITCH MECHANISMREF STRUCTURE V. 16 1562 2008REFN ISSN 0969-2126PMID 18940611DOI 10.1016/J.STR.2008.07.012 Variant Set Distributions Mapped Variants