Assessment of Structural Intolerance and Durability
General Structure Information 3mx7 FAIM crystal structure analysis of human faim-ntd 1.76Å AUTH G.LI,L.QU,G.MENG,X.BAI,K.DAI,X.ZHENGTITL THE STRUCTURE OF HUMAN FAS APOPTOTIC INHIBITORY MOLECULEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1few DIABLO crystal structure of smac/diablo 2.2Å AUTH J.CHAI,C.DU,J.W.WU,S.KYIN,X.WANG,Y.SHITITL STRUCTURAL AND BIOCHEMICAL BASIS OF APOPTOTIC ACTIVATION BYTITL 2 SMAC/DIABLO.REF NATURE V. 406 855 2000REFN ISSN 0028-0836PMID 10972280DOI 10.1038/35022514 Variant Set Distributions Mapped Variants
General Structure Information 3dcy C12orf5 crystal structure a tp53-induced glycolysis and apoptosis regulator protein from homo sapiens. 1.75Å AUTH J.G.MCCOY,C.A.BINGMAN,G.E.WESENBERG,AUTH 2 G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE A TP53-INDUCED GLYCOLYSIS ANDTITL 2 APOPTOSIS REGULATOR PROTEIN FROM HOMO SAPIENS.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2rmn TP63 the solution structure of the p63 dna-binding domain -1.0Å AUTH A.ENTHART,J.FURRER,A.DEHNER,H.KESSLERTITL SOLUTION STRUCTURE AND BINDING STUDIES OF THE P63TITL 2 DNA BINDING DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2y9t TP63 structural basis of p63a sam domain mutants involved in aec syndrome -1.0Å AUTH A.SATHYAMURTHY,S.M.V.FREUND,C.M.JOHNSON,M.D.ALLEN,M.BYCROFTTITL STRUCTURAL BASIS OF P63ALPHA SAM DOMAIN MUTANTS INVOLVED INTITL 2 AEC SYNDROME.REF FEBS J. V. 278 2680 2011REFN ISSN 1742-464XPMID 21615690DOI 10.1111/J.1742-4658.2011.08194.X Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1x5m CACYBP solution structure of the core domain of calcyclin binding protein; siah-interacting protein (sip) -1.0Å AUTH X.R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CORE DOMAIN OF CALCYCLINTITL 2 BINDING PROTEIN; SIAH-INTERACTING PROTEIN (SIP)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3i2n WDR92 crystal structure of wd40 repeats protein wdr92 1.95Å AUTH C.XU,J.MINTITL STRUCTURE AND FUNCTION OF WD40 DOMAIN PROTEINS.REF PROTEIN CELL V. 2 202 2011REFN ISSN 1674-800XPMID 21468892DOI 10.1007/S13238-011-1018-1 Variant Set Distributions Mapped Variants
General Structure Information 1xb0 BIRC8 structure of the bir domain of iap-like protein 2 2.2Å AUTH H.SHIN,M.RENATUS,B.P.ECKELMAN,V.A.NUNES,AUTH 2 C.A.M.SAMPAIO,G.S.SALVESENTITL THE BIR DOMAIN OF IAP-LIKE PROTEIN 2 ISTITL 2 CONFORMATIONALLY UNSTABLE: IMPLICATIONS FORTITL 3 CASPASE INHIBITIONREF BIOCHEM.J. V. 385 1 2005REFN ISSN 0264-6021PMID 15485395DOI 10.1042/BJ20041107 Variant Set Distributions Mapped Variants
General Structure Information 3v6a API5 helical repeat structure of apoptosis inhibitor 5 reveals protein- protein interaction modules 2.6Å AUTH B.G.HAN,K.H.KIM,S.J.LEE,K.C.JEONG,J.W.CHO,K.H.NOH,T.W.KIM,AUTH 2 S.J.KIM,H.J.YOON,S.W.SUH,S.H.LEE,B.I.LEETITL HELICAL REPEAT STRUCTURE OF APOPTOSIS INHIBITOR 5 REVEALSTITL 2 PROTEIN-PROTEIN INTERACTION MODULES.REF J.BIOL.CHEM. V. 287 10727 2012REFN ISSN 0021-9258PMID 22334682DOI 10.1074/JBC.M111.317594 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3qf2 NLRP3 crystal structure of nalp3 pyd 1.7Å AUTH J.Y.BAE,H.H.PARKTITL CRYSTAL STRUCTURE OF NALP3 PROTEIN PYRIN DOMAIN (PYD) ANDTITL 2 ITS IMPLICATIONS IN INFLAMMASOME ASSEMBLYREF J.BIOL.CHEM. V. 286 39528 2011REFN ISSN 0021-9258PMID 21880711DOI 10.1074/JBC.M111.278812 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants