3V6A.A | API5

General Structure Information

PDB ID 3v6a
HGNC Gene Label(s) API5
Structure Name helical repeat structure of apoptosis inhibitor 5 reveals protein- protein interaction modules
Resolution 2.6Å
Reference AUTH B.G.HAN,K.H.KIM,S.J.LEE,K.C.JEONG,J.W.CHO,K.H.NOH,T.W.KIM,AUTH 2 S.J.KIM,H.J.YOON,S.W.SUH,S.H.LEE,B.I.LEETITL HELICAL REPEAT STRUCTURE OF APOPTOSIS INHIBITOR 5 REVEALSTITL 2 PROTEIN-PROTEIN INTERACTION MODULES.REF J.BIOL.CHEM. V. 287 10727 2012REFN ISSN 0021-9258PMID 22334682DOI 10.1074/JBC.M111.317594

Variant Set Distributions

ExAC Variants

Number Of Residues 424
Number Of SNVs 62
Number Of Permutations 24794
Optimal Distance Threshold 27.0
K Statistic 0.302
p-value 0.037
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 62
Number Of COSMIC SNVs 4
Optimal Distance Threshold 48.0
K Statistic 0.32
p-value 0.391

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants