Assessment of Structural Intolerance and Durability
General Structure Information 3u3f PTK2B structural basis for the interaction of pyk2 pat domain with paxillin ld motifs 3.1Å AUTH M.S.VANAROTTI,D.J.MILLER,C.D.GUIBAO,A.NOURSE,J.J.ZHENGTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO THE INTERACTIONTITL 2 BETWEEN PYK2 AND PAXILLIN LD MOTIFS.REF J.MOL.BIOL. V. 426 3985 2014REFN ISSN 0022-2836PMID 25174335DOI 10.1016/J.JMB.2014.08.014 Variant Set Distributions Mapped Variants
General Structure Information 1xm9 PKP1 structure of the armadillo repeat domain of plakophilin 1 2.8Å AUTH H.J.CHOI,W.I.WEISTITL STRUCTURE OF THE ARMADILLO REPEAT DOMAIN OFTITL 2 PLAKOPHILIN 1.REF J.MOL.BIOL. V. 346 367 2005REFN ISSN 0022-2836PMID 15663951DOI 10.1016/J.JMB.2004.11.048 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3f7p PLEC crystal structure of a complex between integrin beta4 and plectin 2.75Å AUTH J.M.DE PEREDA,M.P.LILLO,A.SONNENBERGTITL STRUCTURAL BASIS OF THE INTERACTION BETWEENTITL 2 INTEGRIN ALPHA6BETA4 AND PLECTIN AT THETITL 3 HEMIDESMOSOMESREF EMBO J. V. 28 1180 2009REFN ISSN 0261-4189PMID 19242489DOI 10.1038/EMBOJ.2009.48 Variant Set Distributions Mapped Variants
General Structure Information 4hi9 ILK 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain collected at wavelength 0.91974 1.2Å AUTH A.L.STIEGLER,J.JAKONCIC,V.STOJANOFF,B.P.CHISWELL,AUTH 2 D.A.CALDERWOOD,T.J.BOGGONTITL 1.2 STRUCTURE OF INTEGRIN-LINKED KINASE ANKYRIN REPEATTITL 2 DOMAIN IN COMPLEX WITH PINCH1 LIM1 DOMAIN COLLECTED ATTITL 3 WAVELENGTH 0.91974REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n1p IHH crystal structure of ihhn bound to bocfn3 2.7Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants