Assessment of Structural Intolerance and Durability
General Structure Information 2dit HTATSF1 solution structure of the rrm_1 domain of hiv tat specific factor 1 variant -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RRM_1 DOMAIN OF HIV TATTITL 2 SPECIFIC FACTOR 1 VARIANTREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2fic BIN1 the crystal structure of the bar domain from human bin1/amphiphysin ii and its implications for molecular recognition 1.99Å AUTH E.CASAL,L.FEDERICI,W.ZHANG,J.FERNANDEZ-RECIO,E.M.PRIEGO,AUTH 2 R.N.MIGUEL,J.B.DUHADAWAY,G.C.PRENDERGAST,B.F.LUISI,E.D.LAUETITL THE CRYSTAL STRUCTURE OF THE BAR DOMAIN FROM HUMANTITL 2 BIN1/AMPHIPHYSIN II AND ITS IMPLICATIONS FOR MOLECULARTITL 3 RECOGNITIONREF BIOCHEMISTRY V. 45 12917 2006REFN ISSN 0006-2960PMID 17059209DOI 10.1021/BI060717K […]
General Structure Information 4aif AIP aip tpr domain in complex with human hsp90 peptide 2.01Å AUTH R.M.MORGAN,L.C.HERNANDEZ-RAMIREZ,G.TRIVELLIN,L.ZHOU,S.M.ROE,AUTH 2 M.KORBONITS,C.PRODROMOUTITL STRUCTURE OF THE TPR DOMAIN OF AIP: LACK OF CLIENT PROTEINTITL 2 INTERACTION WITH THE C-TERMINAL ALPHA-7 HELIX OF THE TPRTITL 3 DOMAIN OF AIP IS SUFFICIENT FOR PITUITARY ADENOMATITL 4 PREDISPOSITION.REF PLOS ONE V. 7 […]
General Structure Information 2dnc PDHX solution structure of rsgi ruh-054, a lipoyl domain from human 2-oxoacid dehydrogenase -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.HIROTA,F.HAYASHI,C.KUROSAKI,AUTH 2 M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-054, A LIPOYLTITL 2 DOMAIN FROM HUMAN 2-OXOACID DEHYDROGENASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2vpd BCL9 decoding of methylated histone h3 tail by the pygo-bcl9 wnt signaling complex 2.77Å AUTH M.FIEDLER,M.J.SANCHEZ-BARRENA,M.NEKRASOV,AUTH 2 J.MIESZCZANEK,V.RYBIN,J.MULLER,P.EVANS,M.BIENZTITL DECODING OF METHYLATED HISTONE H3 TAIL BY THETITL 2 PYGO- BCL9 WNT SIGNALING COMPLEX.REF MOL.CELL V. 30 507 2008REFN ISSN 1097-2765PMID 18498752DOI 10.1016/J.MOLCEL.2008.03.011 Variant Set Distributions Mapped Variants
General Structure Information 1wwy TXNL1 solution structure of the duf1000 domain of a thioredoxin-like protein 1 -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,A.TANAKA,AUTH 2 S.SUGANO,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL DUF1000 DOMAIN OF THETITL 2 HUMAN THIOREDOXIN-LIKE 1 PROTEIN.REF PROTEINS V. 78 2176 2010REFN ISSN 0887-3585PMID 20455272DOI 10.1002/PROT.22719 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2d8k SYT7 solution structure of the first c2 domain of synaptotagmin vii -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OFTITL 2 SYNAPTOTAGMIN VIIREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2per CLIC2 crystal structure of human chloride intracellular channel protein 2 2.0Å AUTH W.MI,Y.H.LIANG,L.LI,X.D.SUTITL THE CRYSTAL STRUCTURE OF HUMAN CHLORIDETITL 2 INTRACELLULAR CHANNEL PROTEIN 2: A DISULFIDE BONDTITL 3 WITH FUNCTIONAL IMPLICATIONS.REF PROTEINS V. 71 509 2008REFN ISSN 0887-3585PMID 18186468DOI 10.1002/PROT.21922 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3vkm LGALS8 protease-resistant mutant form of human galectin-8 in complex with sialyllactose and lactose 2.98Å AUTH H.YOSHIDA,S.YAMASHITA,M.TERAOKA,A.ITOH,S.NAKAKITA,N.NISHI,AUTH 2 S.KAMITORITITL X-RAY STRUCTURE OF A PROTEASE-RESISTANT MUTANT FORM OF HUMANTITL 2 GALECTIN-8 WITH TWO CARBOHYDRATE RECOGNITION DOMAINSREF FEBS J. V. 279 3937 2012REFN ISSN 1742-464XPMID 22913484DOI 10.1111/J.1742-4658.2012.08753.X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3ibj PDE2A x-ray structure of pde2a 3.02Å AUTH J.PANDIT,M.D.FORMAN,K.F.FENNELL,K.S.DILLMAN,F.S.MENNITITITL MECHANISM FOR THE ALLOSTERIC REGULATION OF PHOSPHODIESTERASETITL 2 2A DEDUCED FROM THE X-RAY STRUCTURE OF A NEAR FULL-LENGTHTITL 3 CONSTRUCT.REF PROC.NATL.ACAD.SCI.USA V. 106 18225 2009REFN ISSN 0027-8424PMID 19828435DOI 10.1073/PNAS.0907635106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants