3L5K.A | HDHD1

General Structure Information 3l5k HDHD1 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) 2.0Å AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]

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3L5K.A | HDHD1

General Structure Information 3l5k HDHD1 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) 2.0Å AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]

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3L5K.A | HDHD1

General Structure Information 3l5k HDHD1 the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) 2.0Å AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]

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2PON.B | BCL2L1

General Structure Information 2pon BCL2L1 solution structure of the bcl-xl/beclin-1 complex -1.0Å AUTH W.FENG,S.HUANG,H.WU,M.ZHANGTITL MOLECULAR BASIS OF BCL-XLS TARGET RECOGNITIONTITL 2 VERSATILITY REVEALED BY THE STRUCTURE OF BCL-XL INTITL 3 COMPLEX WITH THE BH3 DOMAIN OF BECLIN-1.REF J.MOL.BIOL. V. 372 223 2007REFN ISSN 0022-2836PMID 17659302DOI 10.1016/J.JMB.2007.06.069 Variant Set Distributions Mapped Variants

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1SO2.D | PDE3B

General Structure Information 1so2 PDE3B catalytic domain of human phosphodiesterase 3b in complex with a dihydropyridazine inhibitor 2.4Å AUTH G.SCAPIN,S.B.PATEL,C.CHUNG,J.P.VARNERIN,AUTH 2 S.D.EDMONDSON,A.MASTRACCHIO,E.R.PARMEE,S.B.SINGH,AUTH 3 J.W.BECKER,L.H.VAN DER PLOEG,M.R.TOTATITL CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 3B:TITL 2 ATOMIC BASIS FOR SUBSTRATE AND INHIBITORTITL 3 SPECIFICITYREF BIOCHEMISTRY V. 43 6091 2004REFN ISSN 0006-2960PMID 15147193DOI 10.1021/BI049868I Variant Set Distributions Ripley’s K […]

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1YWH.E | PLAUR

General Structure Information 1ywh PLAUR crystal structure of urokinase plasminogen activator receptor 2.7Å AUTH P.LLINAS,M.H.LE DU,H.GARDSVOLL,K.DANO,M.PLOUG,B.GILQUIN,AUTH 2 E.A.STURA,A.MENEZTITL CRYSTAL STRUCTURE OF THE HUMAN UROKINASE PLASMINOGENTITL 2 ACTIVATOR RECEPTOR BOUND TO AN ANTAGONIST PEPTIDEREF EMBO J. V. 24 1655 2005REFN ISSN 0261-4189PMID 15861141DOI 10.1038/SJ.EMBOJ.7600635 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]

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2CQI.A | TIAL1

General Structure Information 2cqi TIAL1 solution structure of the rna binding domain of nucleolysin tiar -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN OF NUCLEOLYSINTITL 2 TIARREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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4I5K.B | PPP2R3A

General Structure Information 4i5k PPP2R3A pp2a pr70 holoenzyme model3_dica_rcsb.pdb bppnat5_extend.mtz 2.9Å AUTH N.WLODARCHAK,F.GUO,K.A.SATYSHUR,L.JIANG,P.D.JEFFREY,T.SUN,AUTH 2 V.STANEVICH,M.C.MUMBY,Y.XINGTITL STRUCTURE OF THE CA(2+)-DEPENDENT PP2A HETEROTRIMER ANDTITL 2 INSIGHTS INTO CDC6 DEPHOSPHORYLATION.REF CELL RES. V. 23 931 2013REFN ISSN 1001-0602PMID 23752926DOI 10.1038/CR.2013.77 Variant Set Distributions Mapped Variants

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2OKK.A | GAD2

General Structure Information 2okk GAD2 the x-ray crystal structure of the 65kda isoform of glutamic acid decarboxylase (gad65) 2.3Å AUTH G.FENALTI,R.H.LAW,A.M.BUCKLE,C.LANGENDORF,K.TUCK,C.J.ROSADO,AUTH 2 N.G.FAUX,K.MAHMOOD,C.S.HAMPE,J.P.BANGA,M.WILCE,AUTH 3 J.SCHMIDBERGER,J.ROSSJOHN,O.EL-KABBANI,R.N.PIKE,A.I.SMITH,AUTH 4 I.R.MACKAY,M.J.ROWLEY,J.C.WHISSTOCKTITL GABA PRODUCTION BY GLUTAMIC ACID DECARBOXYLASE IS REGULATEDTITL 2 BY A DYNAMIC CATALYTIC LOOP.REF NAT.STRUCT.MOL.BIOL. V. 14 280 2007REFN ISSN 1545-9993PMID 17384644DOI 10.1038/NSMB1228 Variant Set Distributions Ripley’s K […]

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1FVR.A | TEK

General Structure Information 1fvr TEK tie2 kinase domain 2.2Å AUTH L.M.SHEWCHUK,A.M.HASSELL,B.ELLIS,W.D.HOLMES,AUTH 2 R.DAVIS,E.L.HORNE,S.H.KADWELL,D.D.MCKEE,J.T.MOORETITL STRUCTURE OF THE TIE2 RTK DOMAIN: SELF-INHIBITIONTITL 2 BY THE NUCLEOTIDE BINDING LOOP, ACTIVATION LOOP,TITL 3 AND C-TERMINAL TAIL.REF STRUCTURE FOLD.DES. V. 8 1105 2000REFN ISSN 0969-2126PMID 11080633DOI 10.1016/S0969-2126(00)00516-5 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants

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