General Structure Information
| PDB ID | 1ywh |
| HGNC Gene Label(s) | PLAUR |
| Structure Name | crystal structure of urokinase plasminogen activator receptor |
| Resolution | 2.7Å |
| Reference | AUTH P.LLINAS,M.H.LE DU,H.GARDSVOLL,K.DANO,M.PLOUG,B.GILQUIN,AUTH 2 E.A.STURA,A.MENEZTITL CRYSTAL STRUCTURE OF THE HUMAN UROKINASE PLASMINOGENTITL 2 ACTIVATOR RECEPTOR BOUND TO AN ANTAGONIST PEPTIDEREF EMBO J. V. 24 1655 2005REFN ISSN 0261-4189PMID 15861141DOI 10.1038/SJ.EMBOJ.7600635 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 262 |
| Number Of SNVs | 75 |
| Number Of Permutations | 31673 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.188 |
| p-value | 0.392 |
COSMIC
| Number Of Residues | 262 |
| Number Of SNVs | 4 |
| Number Of Permutations | 196 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.167 |
| p-value | 0.971 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 75 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.19 |
| p-value | 0.942 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
