General Structure Information
| PDB ID | 3l5k |
| HGNC Gene Label(s) | HDHD1 |
| Structure Name | the crystal structure of human haloacid dehalogenase-like hydrolase domain containing 1a (hdhd1a) |
| Resolution | 2.0Å |
| Reference | AUTH E.UGOCHUKWU,K.GUO,S.PICAUD,J.MUNIZ,C.ALLERSTON,AUTH 2 F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,W.W.YUE,K.L.KAVANAGH,U.OPPERMANN,AUTH 4 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE CRYSTAL STRUCTURE OF HUMAN HALOACIDTITL 2 DEHALOGENASE-LIKE HYDROLASE DOMAIN CONTAINING 1ATITL 3 (HDHD1A)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 228 |
| Number Of SNVs | 47 |
| Number Of Permutations | 7224 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.009 |
| p-value | 0.02 |
COSMIC
| Number Of Residues | 228 |
| Number Of SNVs | 4 |
| Number Of Permutations | 725 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.461 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.144 |
| p-value | 0.463 |